“…However, PSA levels of >10 ng/ml, and high Gleason grade (>7) are associated with an increased risk of progression as determined by PSA failure (i.e. detectable PSA) after radical prostatectomy [7, 16, 17, 18, 19, 20, 21]. Other pathological risk factors include high clinical stage, positive surgical margins, the presence of extracapsular disease, seminal vesicle invasion, or involvement of pelvic lymph nodes (i.e.…”