A Multicentre Double Blind, Placebo Controlled Randomized Trial to Evaluate the Safety and Efficacy of Bovine Colostrum in the Treatment of Severe Alcoholic Hepatitis (SAH).
Abstract:Background
Alcoholic Hepatitis (AH) in patients of 2 contemporary Randomized Controlled Trials in India was extremely severe: Maddrey’s Discriminant Function (mDF) [score of 77.4–84 ; MELD of 26–27.5]. The survival rate was very low: 22–30.4%. A pilot study from our group had recently treated ten patients with Severe Alcoholic Hepatitis (SAH) with Bovine colostrum (BC) [20 g thrice in a day for eight weeks] and prednisolone [40 mg once a day for four weeks, tapered over four weeks]. This combo therapy improved… Show more
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