A multicenter study of genotype variation/demographic patterns in 2475 individuals inluding with 1444 cases with breast cancer in Turkey Short Title: BRCA profiling of breast-cancer patients in Turkey
Abstract:BACKGROUND
Breast Cancer is the most common cancer type in women, second among the all cancers, and inherited with autosomal dominant pattern. The clinical diagnosis of BC relies on the published diagnostic criteria, and two genes have been identified as the main causative for breast cancer which are BRCA1 and BRCA2.
OBJECTIVE
We aimed to compare the index cases with the diagnostic features to describe the genotype/demographic information association in breast cancer.
METHODS
We performed mutational analyse… Show more
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