A Multicenter Randomized Noninferiority Trial Comparing GreenLight-XPS Laser Vaporization of the Prostate and Transurethral Resection of the Prostate for the Treatment of Benign Prostatic Obstruction: Two-yr Outcomes of the GOLIATH Study

Thomas, James A.; Tubaro, Andrea; Barber, Neil; d’Ancona, Frank A.; Muir, Gordon; Witzsch, U.; Grimm, Marc‐Oliver; Benejam, Joan; Stolzenburg, Jens‐Uwe; Riddick, Antony C. P.; Pahernik, Sascha; Roelink, Herman; Ameye, Filip; Saussine, C.; Bruyère, F.; Loidl, Wolfgang; Larner, Tim; Gogoi, Nirjan-Kumar; Hindley, Richard G.; Muschter, R.; Thorpe, Andrew; Shrotri, Nitin; Graham, Stuart; Hamann, Moritz; Miller, Kurt; Schostak, Martin; Capitán, Carlos; Knispel, Helmut H.; Bachmann, Alexander

doi:10.1016/j.eururo.2015.07.054

Cited by 213 publications

(139 citation statements)

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“…16,17 More recent studies have demonstrated excellent outcome of 180W XPS GL PVP over a period of 2 years. 6 The current study is unique as it is the first study to the best of our knowledge to report 5-year durability outcomes. To note, only 66 patients (out of 370) had a complete 5-year follow up.…”

Section: Cuaj -Original Research Ajib Et Al Long-term Outcomes With 1mentioning

confidence: 99%

“…Similar As mentioned previously, the Goliath study is the only prospective randomized clinical trial comparing 180W XPS and TURP with an exclusion of any patient in urinary retention. 6 At 2 years, they reported an IPSS score of 6.9, which suggests a drop of 14.3 points (67.5%) form baseline (21.2 points). Moreover, in our study preoperatively, the IPSS was 26.2 points with 46% of patients in urinary retention at the time of surgery.…”

Section: Cuaj -Original Research Ajib Et Al Long-term Outcomes With 1mentioning

confidence: 99%

“…6,9,10 However, durability outcomes have been questioned for the initial 80W and 120W generation systems. 9 Despite the 180W…”

Section: Introductionmentioning

confidence: 99%

“…4,5 Over the past decades, Greenlight (GL) 532nm-laser photo selective vaporization of the prostate (PVP) has gained widespread acceptance as a safe and effective alternative to TURP. 3,6 This technology is based on a 532 nm length laser that vaporizes the highly vascularised transitional prostatic zone by selectively heating the hemoglobin. 7,8 In the year 2000, the first laser 80W KTP laser was commercialized.…”

Section: Introductionmentioning

confidence: 99%

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Photoselective vaporization of the prostate with the 180-W XPSGreenlight laser: Five-year experience of safety, efficiency, and functional outcomes

Ajib

Mansour

Zanaty

et al. 2018

CUAJ

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Introduction: Transurethral resection of the prostate (TURP) is still considered the gold standard surgical treatment for symptomatic benign prostatic hyperplasia (BPH). However, photoselective vaporization of the prostate (PVP) has gained widespread global acceptance in national guidelines as a safe and effective alternative option. Nevertheless, further evidence is required to assess the durability of Greenlight PVP. Herein, we reported our five years PVP experience with the Greenlight 180W XPS laser system. Methods: A retrospective analysis was conducted on a prospectively gathered database of 370 consecutive included patients who underwent PVP using Greenlight XPS-180 W laser system (Boston Scientific, Boston, MA, U.S.) performed by a single experienced laser surgeon between 2011 and 2016. Preoperative characteristics, intervention parameters, postoperative functional, uroflowmetry outcomes, and complications were collected. Outcomes are reported over a period of five years. Results: Mean age was 68 years with a mean prostate volume of 78.8 cc (95% confidence interval [CI] 70.9-78.7]). The mean followup was 59.4 months (55.4-63.5). Mean energy, operative time and energy/cc were 270.2 kJ (255.2-285.2), 62.7 minutes (59.6-65.7), and 3.7 kJ/cc (3.6-3.9), respectively. Compared to preoperative values, International Prostate Symptom Score (IPSS), maximum flow rate (Qmax), and post-void residual (PVR) parameters were significantly improved and sustained over the five postoperative years. To note, only 66 patients (out of 370) had a complete five-year

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Section: Cuaj -Original Research Ajib Et Al Long-term Outcomes With 1mentioning

confidence: 99%

Section: Cuaj -Original Research Ajib Et Al Long-term Outcomes With 1mentioning

confidence: 99%

“…6,9,10 However, durability outcomes have been questioned for the initial 80W and 120W generation systems. 9 Despite the 180W…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Photoselective vaporization of the prostate with the 180-W XPSGreenlight laser: Five-year experience of safety, efficiency, and functional outcomes

Ajib

Mansour

Zanaty

et al. 2018

CUAJ

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“…Neben der TUR-P, die als Goldstandard zur Deobstruktion der Prostata gilt, gibt es auch neuere alternativen Verfahren wie zum Beispiel die transurethrale LASER-oder Plasma-Vaporisation der Prostata mit bis anhin ähnlichen postoperativen Ergebnissen im mittelfristigen Verlauf [18,19]. Bei minimalinvasiven Verfahren wie zum Beispiel dem UroLift, ist die Datenlage zu den postoperativen Ergebnissen aktuell ungenügend [20].…”

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Urininkontinenz beim Mann – ein Tabuthema

Kozomara-Hocke

Hermanns

Poyet

2016

Praxis

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Male urinary incontinence is an underestimated and frequently not broached issue. The urinary incontinence is divided into stress-, urge incontinence and hybrid forms as well as overflow incontinence. The fact that there are increasingly more men over 60 means that the prevalence of the urinary incontinence is up to 40%, and urinary incontinence will increasingly gain importance in daily routine practice. Many investigations and therapies can be realized by the general practitioner. Already simple therapy approaches can lead to a considerable clinical improvement of male urinary incontinence. If the initial therapy fails or pathological results (i. e. microhaematuria, recurrent urinary tract infections, raised residual urine and so on) are found, the patient should be referred to a urologist. Si la thérapie primaire ne réussit pas à résoudre l'incontinence urinaire ou on trouve des résultats pathologique (hématurie microscopique, infection urinaire récidivé, urine résiduelle augmenté etc.) le patient doit être envoyé chez le spécialiste d'urologie.4

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532 nm High‐power Transurethral Laser Prostatectomy

Chughtai

Thomas

2018

Smith's Textbook of Endourology

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A Multicenter Randomized Noninferiority Trial Comparing GreenLight-XPS Laser Vaporization of the Prostate and Transurethral Resection of the Prostate for the Treatment of Benign Prostatic Obstruction: Two-yr Outcomes of the GOLIATH Study

Cited by 213 publications

References 10 publications

Photoselective vaporization of the prostate with the 180-W XPSGreenlight laser: Five-year experience of safety, efficiency, and functional outcomes

Photoselective vaporization of the prostate with the 180-W XPSGreenlight laser: Five-year experience of safety, efficiency, and functional outcomes

Urininkontinenz beim Mann – ein Tabuthema

532 nm High‐power Transurethral Laser Prostatectomy

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