A multicenter phase II study of sequential vinorelbine and cisplatin followed by docetaxel and gemcitabine in patients with advanced non-small cell lung cancer

Pallis, Athanasios; Agelidou, Athina; Papakotoulas, Pavlos; Tsaroucha, Angeliki; Agelidou, M.; Agelaki, Sofia; Androulakis, Nikolaos; Vamvakas, L.; Gerogianni, Aleka; Κotsakis, Athanasios; Kentepozidis, Nikolaos

doi:10.1016/j.lungcan.2006.01.005

Cited by 6 publications

(1 citation statement)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When sequential chemotherapy offered, it is possible to overcome the drug resistance of single regimen used for a relatively longer period. Actually, the debate about maintenance therapy for advanced NSCLC had been re-ignited in recent years (Hosoe et al, 2003;Grossi et al, 2004;Chiappori et al, 2005;Pallis et al, 2006). The results of several randomized phase III studies reported showing a significant advantage of maintenance treatment in advanced NSCLC (Ciuleanu et al, 2007;Fidias et al, 2009;Cappuzzo et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Triplet Platinum-based Combination Sequential Chemotherapy Improves Survival Outcome and Quality of Life of Advanced Non-small Cell Lung Cancer Patients

Chen¹,

Liang²,

Yang³

et al. 2012

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Background: Maintenance chemotherapy is one strategy pursued in recent years with intent to break through the chemotherapy plateau for advanced non-small cell lung cancer (NSCLC). However, given the toxicity, platinum-based combinations are rarely given for this purpose. We carried out the present prospective study of triplet platinum-based combination sequential chemotherapy in advanced NSCLC to investigate if patients could tolerate and benefit from such intensive treatment.

show abstract