A multi-residue electrochemical biosensor based on graphene/chitosan/parathion for sensitive organophosphorus pesticides detection

Xie, Xiaomin; Zhou, Binhua P.; Zhang, Yonglei; Zhao, Guozheng; Zhao, Bo

doi:10.1016/j.cplett.2021.138355

Cited by 36 publications

(9 citation statements)

References 28 publications

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“…This allows the sensor to be prepared for the appropriate application. Electrochemical biosensors are also widely used outside the analysis of DNA–molecule interactions in the detection and quantification of chemicals such as drugs, metabolites, pollutants, biomarkers etc [ 69 , 74 , 75 , 76 , 77 , 78 ].…”

Section: Electrochemical Approach To Dna–drug Interaction Descriptionmentioning

confidence: 99%

What Can Electrochemical Methods Offer in Determining DNA–Drug Interactions?

2021

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The interactions of compounds with DNA have been studied since the recognition of the role of nucleic acid in organisms. The design of molecules which specifically interact with DNA sequences allows for the control of the gene expression. Determining the type and strength of such interaction is an indispensable element of pharmaceutical studies. Cognition of the therapeutic action mechanisms is particularly important for designing new drugs. Owing to their sensitivity, simplicity, and low costs, electrochemical methods are increasingly used for this type of research. Compared to other techniques, they require a small number of samples and are characterized by a high reliability. These methods can provide information about the type of interaction and the binding strength, as well as the damage caused by biologically active molecules targeting the cellular DNA. This review paper summarizes the various electrochemical approaches used for the study of the interactions between pharmaceuticals and DNA. The main focus is on the papers from the last decade, with particular attention on the voltammetric techniques. The most preferred experimental approaches, the electrode materials and the new methods of modification are presented. The data on the detection ranges, the binding modes and the binding constant values of pharmaceuticals are summarized. Both the importance of the presented research and the importance of future prospects are discussed.

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Section: Electrochemical Approach To Dna–drug Interaction Descriptionmentioning

confidence: 99%

What Can Electrochemical Methods Offer in Determining DNA–Drug Interactions?

2021

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“…18 Electrochemical technology for OPPs detection has received extensive attention in recent years. 19,20 Most electrochemical methods for detecting OPPs are based on enzyme inhibition, and the most commonly used enzyme is acetylcholinesterase (AChE). 21 AChE is extracted from animal tissues and organs, 22 such as the head of the housefly, the electric organ of the electric eel, and horse serum and duck plasma.…”

Section: Introductionmentioning

confidence: 99%

A novel electrochemical sensing platform based on the esterase extracted from kidney bean for high-sensitivity determination of organophosphorus pesticides

Tao

et al. 2022

RSC Adv.

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“…Organophosphorus (OPPs) is a kind of compound used in agriculture to prevent pests and weeds. Because of high control efficiency and short half-life, the OPPs is extensively used ( Xie, Zhou, Zhang, Zhao & Zhao, 2021 ). Unfortunately, excessive use of OPPs cause it to remain in water or soil, and the residues impact non-target organisms negatively through entry into the food chain.…”

Section: Introductionmentioning

confidence: 99%