A multi-ratiometric fluorescence sensor integrated intrinsic signal amplification strategy for a sensitive and visual assay of the anthrax biomarker based on a bimetallic lanthanide metal–organic framework

Abstract

Development of sensitive and prompt approaches for reliable determination of dipicolinic acid (DPA) is of great importance for human health and public security. Herein, we synthesize a bimetallic lanthanide metal-organic...

Red-emissive carbon nanostructure-anchored molecularly imprinted Er-BTC MOF: a biosensor for visual anthrax monitoring

“…[9][10][11] This is mainly due to their minimal device requirement and, in some cases, no device requirement at all, especially in visual applications. 12 The remarkable importance of sensors lies in their ability to enable the engineering of a substrate with a specific design to detect and analyze the desired analyte, particularly under unique or specific conditions. 13,14 From another perspective, the advancement of public health relies on the monitoring of abnormalities in real samples, including body fluids and environmental waters, using biosensors.…”

Portable visual assay for anthrax biomarker based on lanthanide coordination polymer nanoparticles and smartphone-integrated mini-device

“…Fig. 3B shows the good linearity between the ratio (F 545 /F 425 ) of the fluorescence intensity at 545 nm and 425 nm and the concentration of DPA in the range of 0.01-10 μM; the regression equation is F 545 /F 425 = 1.35001[DPA] + 0.1092 (R 2 = 0.9998), and the limit of detection (LOD, 3σ/k) is 3.4 nM, which is much Environmental Science: Nano Paper lower than the dose of DPA (60 μM) produced by the number of contagious spores required to cause anthrax, 38,39 and it is comparable or better than the those of previously reported fluorescence approaches (Table S2 †).…”

Efficient Eu3+-Integrated UiO-66 Probe for Ratiometric Fluorescence Sensing of Styrene and Cyclohexanone

“…These weaknesses can be overcome by introducing a second referring emission into the ratio fluorescence sensor . Thus, calculating the ratio of fluorescence emission intensities at two wavelengths minimizes interferences, affording high sensitivity toward chemical targets. ,, Recently, MOF-based ratio fluorescence (self-calibrating or self-referencing) sensors have been reported for identifying styrene, temperature, ions, and biomolecules. ,,− For instance, Li et al explored PO 4 3– and acetylacetone detection using a dual luminescent europium MOF {[Eu­(bcpt)­(HCOO)] 0.5 H 2 O} n chemosensor. Limits of detection (LODs) were 0.274 and 0.121 mM, respectively.…”