A Multi-channel platform for recording and stimulation of large neuronal structures

The genetic absence epilepsy rat from Strasbourg as a model to decipher the neuronal and network mechanisms of generalized idiopathic epilepsies

“…This required to implement an online SWDs detection algorithm based on permutation entropy (Li et al, 2007) that was coupled to an integrated electronic device allowing multi-site recording and programmable stimulations (Guillemaud et al, 2009). In this study, we obtained 100% of sensibility of the seizure detection algorithm thanks to the robust reproducibility of SWD.…”

“…Indeed, modern radiosurgical devices such as Gamma Knife® and Cyberknife® (Régis et al, 2006) (Guillemaud et al, 2009). Activity in S1 was continuously monitored and quantified using permutation entropy.…”

Commercialisation of CMOS Integrated Circuit Technology in Multi-Electrode Arrays for Neuroscience and Cell-Based Biosensors

“…Ayanda produce square (40 × 40 μm) platinum electrodes with typical impedances of 400–600 kΩ (at 1 kHz). In partnership with Bio-Logic SAS (France), Ayanda also produce passive MEAs with up to 256 electrodes [ 104 ]. Alpha Med Scientific, Inc.(Japan), manufacture the MED64 system which comprises 64 electrode MEAs and supporting data acquisition and analysis instrumentation [ 105 ].…”

3D shaped mechanically flexible diamond microelectrode arrays for eye implant applications: The MEDINAS project

“…To cope with these pathologies, innovative therapeutic solutions are still sought. Recent advances in micro and nanotechnology have opened new routes for the fabrication of Micro-Electrode Arrays (MEAs) [1], paving the way to novel treatment strategies using neural implants. Implants can be used to electrically stimulate neural networks to relay an altered neural network to restore lost functions.…”