2021
DOI: 10.3390/app11104321
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A Multi-Channel and Multi-Spatial Attention Convolutional Neural Network for Prostate Cancer ISUP Grading

Abstract: Prostate cancer (PCa) is one of the most prevalent cancers worldwide. As the demand for prostate biopsies increases, a worldwide shortage and an uneven geographical distribution of proficient pathologists place a strain on the efficacy of pathological diagnosis. Deep learning (DL) is able to automatically extract features from whole-slide images of prostate biopsies annotated by skilled pathologists and to classify the severity of PCa. A whole-slide image of biopsies has many irrelevant features that weaken th… Show more

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Cited by 9 publications
(7 citation statements)
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“…Thus, one direction is to simplify the DNN architecture, keeping the model slim and fast. Second, there are other feature extraction techniques to be tested in our system, such as CNN attention modules [59] and feature interaction [60]. Third, a generative data augmentation method can further enrich the vehicle samples in the original dataset.…”
Section: Discussionmentioning
confidence: 99%
“…Thus, one direction is to simplify the DNN architecture, keeping the model slim and fast. Second, there are other feature extraction techniques to be tested in our system, such as CNN attention modules [59] and feature interaction [60]. Third, a generative data augmentation method can further enrich the vehicle samples in the original dataset.…”
Section: Discussionmentioning
confidence: 99%
“…This work has the following limitations that also point out our future research directions. First, the biattention module applied in the attentive feature extractor only employs a single MLP to learn the attentions, while a multichannel and multispatial attention mod-ule [32] can be adopted for further improvement. Second, the attentive feature extractor only considers one image/feature scale, while a multiscale-based feature pyramid can be utilized to encourage the network to extract features in multiple granularities.…”
Section: Discussionmentioning
confidence: 99%
“…The system achieved an accuracy of 89.4% on the internal test set. In Yang et al (Yang & Xiao 2021), a subset of the tiles are selected based on mean pixel value. A Multi-Channel and Multi-Spatial (MCMS) attention mechanism is proposed to be added to any CNN architecture to improve feature extraction and aid the backbone CNN to focus on more relevant areas of the image.…”
Section: Related Workmentioning
confidence: 99%