A multi-centre evaluation of 566 cases of ameloblastoma in Nigeria by the African Oral Pathology Research Consortium

Soyele, Olujide Oladele; Akinshipo, Abdulwarith; Effiom, Olajumoke Ajibola; Omitola, Olufemi Gbenga; Okoh, Dickson Sopuru; Sigbeku, OF; Butali, Azeez; Adeola, Henry Ademola

doi:10.1007/s41548-019-00018-6

Cited by 4 publications

(11 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Younger patients and patients with associated pain typically present earlier, 5,7 but these findings were not replicated in the current study. In an African setting, only 23% of patients presented within the first year of noting the lesion due to difficulty accessing specialised healthcare services in developing countries 22,23 . In the current study, 57% of patients presented within 12 months of noticing the lesion.…”

Section: Discussionmentioning

confidence: 48%

“…In an African setting, only 23% of patients presented within the first year of noting the lesion due to difficulty accessing specialised healthcare services in developing countries. 22,23 In the current study, 57% of patients presented within 12 months of noticing the lesion. Swelling is the most common presenting symptom, followed by pain, fistula formation and tooth mobility.…”

Section: Additionally Global Reports Indicate That Black Patients Pre...mentioning

confidence: 49%

“…In the current study, this might be due to the population group distribution in South Africa. Additionally, global reports indicate that black patients presented with ABs at a much younger age compared to other population groups 7,11,13,22 …”

Section: Discussionmentioning

confidence: 99%

“…7,11,13,22 T A B L E 2 *Highlight statistically significant findings are in bold. a In one-mixed density case, the locularity could not be described.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Clinicoradiologic features of ameloblastomas: A single‐centre study of 155 cases

Smit,

Robinson,

Ker‐Fox

et al. 2024

J Oral Pathology Medicine

View full text Add to dashboard Cite

BackgroundThe purpose of the current study was to report on the clinical presentation and radiologic features of 155 cases of ameloblastoma (AB), representing a detailed, large, single‐centre radiologic study.MethodsHistologically confirmed cases were reviewed over 11 years. Demographic and clinical data were retrieved from the patient's records. Radiologic information was analysed from available radiographs. The radiologic features of ABs were assessed according to the mean age of presentation and the mean duration of the lesion. The distinguishing radiologic features between adults/children and sex were also evaluated.ResultsA statistically significant correlation existed between loss of border demarcation and advanced mean age. Multilocular lesions were markedly more common in adults compared to children. Multilocular ABs were associated with increased lesion duration and advanced mean age. Radiologic signs of reactive bony changes associated with the tumour presented at the highest mean duration of all bony effects. Bony expansion and cortical destruction were statistically correlated with lesion duration. Tooth impaction was more common in children. Some mandibular lesions reached a significant size, resulting in impingement of the maxillary sinus, zygoma, orbit and pterygoid plates.ConclusionDue to unfortunate healthcare access constraints, ABs grow to significant sizes and exhibit features not often reported in the literature. The findings of this analysis highlighted the radiologic features of ABs expressed through the mean age and duration of the lesion. This emphasises the significance of timely management of these lesions.

show abstract

Section: Discussionmentioning

confidence: 48%

Section: Additionally Global Reports Indicate That Black Patients Pre...mentioning

confidence: 49%

Section: Discussionmentioning

confidence: 99%

“…7,11,13,22 T A B L E 2 *Highlight statistically significant findings are in bold. a In one-mixed density case, the locularity could not be described.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Clinicoradiologic features of ameloblastomas: A single‐centre study of 155 cases

Smit,

Robinson,

Ker‐Fox

et al. 2024

J Oral Pathology Medicine

View full text Add to dashboard Cite

show abstract

“…This usually holds true in the conventional variant while the unicystic variant may have a slight male bias [1]. A male predominance of diagnosis has been frequently reported in Nigeria [12][13][14][15][16]. Agbaje et al reported a slight male predominance in a study which pooled data from 10 tertiary hospitals in 5 out of the 6 geopolitical regions of Nigeria [2].…”

Section: Introductionmentioning

confidence: 99%

Demographics and Pathomorphology of Ameloblastoma: A 9 Year Retrospective Review at a Tertiary Health Care Centre in North-Central Nigeria

Akpa,

Emmanuel,

Kwaghe

et al. 2024

View full text Add to dashboard Cite

Ameloblastoma is a benign but locally invasive neoplasm that arises from odontogenic epithelium of the dental lamina. It is classified into the conventional, unicystic, extraosseous/peripheral and metastasizing variants. It is the most common odontogenic tumour in Nigeria and other developing countries. It affects individuals of all ages, has a peak of occurrence in the fourth and fifth decades with no sex predilection. The Mandible is the most commonly affected site and the conventional variant is predominant. The aim of this study is to document the demographics and Pathomorphology of ameloblastoma diagnosed at the Jos University Teaching Hospital over the past nine years. There is no previous documentation of the pattern of this tumour in the North-central region of Nigeria making this study relevant. This is a retrospective observational review of all cases of ameloblastoma diagnosed histologically at the Jos University Teaching Hospital between January 1st 2015 to December 31st 2023. Materials utilized consisted of patient clinical case files, electronic histopathology result records, histopathology glass slides and formalin fixed paraffin embedded tissue blocks. The patient age, sex, anatomic location of tumour in the Jaw/face and pathomorphological features were recorded for all cases. The data obtained was analysed using Epi-info 7 (version 3.5.4) and Microsoft-Excel. Results were presented in tables and charts. Fifty one cases of ameloblastoma were diagnosed during the 9 years of review. Their ages ranged between 6 and 65 years with a mean age of 30.9±13.8 years and a peak of occurrence in the third decade. There were 29 males and 22 females with a male to female ratio (M:F) of 1.3:1. Ninety-two percent of cases occurred in the mandible and 8% in the maxilla. The conventional variant accounted for 72.5% of cases and the unicystic variant 27.5%. The follicular type accounted for 64.8% of cases of conventional ameloblastoma. Ameloblastoma occurred more commonly in males with a peak in the third decade. A vast majority of cases involved the mandible and the conventional type was predominant. This demographic pattern supports existing evidence that ameloblastoma occurs more commonly in males and in relatively younger patients in Africa.

show abstract

Prevalence of Ameloblastoma in Sub-Saharan Africa: A systematic review and meta-analysis

Aborisade,

Okolo,

Akinsanya

et al. 2024

Journal of Stomatology, Oral and Maxillofacial Surgery

View full text Add to dashboard Cite

A multi-centre evaluation of 566 cases of ameloblastoma in Nigeria by the African Oral Pathology Research Consortium

Cited by 4 publications

References 23 publications

Clinicoradiologic features of ameloblastomas: A single‐centre study of 155 cases

Clinicoradiologic features of ameloblastomas: A single‐centre study of 155 cases

Demographics and Pathomorphology of Ameloblastoma: A 9 Year Retrospective Review at a Tertiary Health Care Centre in North-Central Nigeria

Prevalence of Ameloblastoma in Sub-Saharan Africa: A systematic review and meta-analysis

Contact Info

Product

Resources

About