A molecular propeller effect for chiral separation and analysis

Clemens, Jonathon B.; Kibar, Osman; Chachisvilis, Mirianas

doi:10.1038/ncomms8868

Cited by 25 publications

(21 citation statements)

References 33 publications

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“…Clemens and coworkers 27 nevertheless did attempt to perform chiral separation at the molecular scale. To this end, they surrounded a capillary tubing with four electrodes (see Fig.…”

Section: At the Molecular Scalementioning

confidence: 99%

Mechanical chiral resolution

et al. 2019

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“…Clemens and coworkers 27 nevertheless did attempt to perform chiral separation at the molecular scale. To this end, they surrounded a capillary tubing with four electrodes (see Fig.…”

Section: At the Molecular Scalementioning

confidence: 99%

Mechanical chiral resolution

et al. 2019

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“…[22,23] It has been shown that the bi-chiral plasmonic arrays can possess complexly chiroptical responses once the strong coupling occurs between the chiral centers, for example by changing their relative distance to tune their coupling. [22] Inspired by the emerging propeller chirality in molecular systems, [24][25][26][27][28][29] here we report a novel scheme to construct the bi-chiral plasmonic arrays and realize the strong coupling between the chiral centers to achieve the phase enabled circular dichroism reversal. As illustrated in Figure 1a, the proposed RH propeller metamolecules consist of three twisted blades that are connected by a chiral center R. Such an artificial metamolecule mimics well the configuration of propellertype chemical molecules, in which the molecular blades were unidirectionally twisted with respect to the central group.…”

Section: Phase Enabled Circular Dichroism Reversal In Twisted Bi-chiral Propeller Metamolecule Arraysmentioning

confidence: 99%

Phase Enabled Circular Dichroism Reversal in Twisted Bi‐Chiral Propeller Metamolecule Arrays

Chen

et al. 2021

Advanced Optical Materials

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Artificial chiral structures play a crucial role in the realization of strong chiroptical responses and flexible light manipulation. Here, a unique bi‐chiral propeller metamolecule array is demonstrated in which the geometric chirality of the subunit with intracellular blades is opposite to that of the subunit with intercellular blades. Benefited from the special propeller twists, it is demonstrated that the propeller metamolecule arrays support the phase controlled chiral surface lattice resonances, whose amplitude can be tailored by tuning the coupling of chiral centers to change the interference phase. Specifically, the circular dichroism of the metamolecule array is readily reversed by rotating the propeller blades without changing the local geometry and the lattice parameters. The proposed bi‐chiral propeller metamolecule array and the exotic circular dichroism reversal are further demonstrated in experiments by adopting a nano‐kirigami fabrication method. This work provides a novel paradigm to investigate the profound chiroptical responses and manipulate the advanced spin states of light.

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“…In Ref. [13], it was shown that when exposed to a rotating electric field (at the frequency of 900 kHz), the left-and right-handed chiral molecules rotate with the field and act as microscopic propellers. Owing to their opposite handedness, they propel along the axis of field rotation in opposite directions.…”

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confidence: 99%

Microwave chirality discrimination in enantiomeric liquids

Hollander

Kamenetskii

Shavit

2017

Journal of Applied Physics

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Chirality discrimination is of a fundamental interest in biology, chemistry, and metamaterial studies. In optics, near-field plasmon-resonance spectroscopy with superchiral probing fields is effectively applicable for analyses of large biomolecules with chiral properties. We show possibility for microwave near-field chirality discrimination analysis based on magnon-resonance spectroscopy. Newly developed capabilities in microwave sensing using magnetoelectric (ME) probing fields originated from multiresonance magnetic-dipolar-mode (MDM) oscillations in quasi-2D yttrium-irongarnet (YIG) disks, provide a potential for unprecedented measurements of chemical and biological objects. We report on microwave near-field chirality discrimination for aqueous D-and L-glucose solutions. The shown ME-field sensing is addressed to microwave biomedical diagnostics and pathogen detection and to deepening our understanding of microwave-biosystem interactions. It can be also important for an analysis and design of microwave chiral metamaterials.Many molecules in chemistry and biology are chiral. Biologically active molecules in amino acids (the building blocks of proteins) and sugars are chiral molecules. Chiral discrimination in a mixture of chiral molecules is among the most important and difficult tasks in biophysics and chemistry. In this connection, development of a technique that offers improved chiral analysis and better understanding of interactions of electromagnetic fields with chiral materials remains an important goal. Traditional chiroptical spectroscopy arises from the effect of interference between the electric-dipole transition moment and the weak magnetic-dipole transition moment that is detected when a chiral molecule is irradiated with alternating right-or left-circularly polarized light [1 -3]. For localized (subwavelength) chiroptical biosensing, special plasmonic structures with left-and right-handed superchiral probing fields are effectively used [4 -6].The measured forms of chiroptical intensity are inversely proportional to the wavelength of the probing radiation. That is why use of microwave radiation to detect chirality was considered as a non-solvable problem. Surprisingly, a new microwave technique based on chirality-sensitive three-wave mixing to identify the enantiomers of chiral molecules, was demonstrated in Ref. [7]. This technique departs from traditional (optical) electromagnetic methods for detecting and identifying the handedness of molecules. Because it does not depend on a weak magnetic-dipole transition moment, the chiral signal is nearly as large as that of the applied microwaves. This conceptually new method to detect chirality is applicable, however, to cold gas-phase molecules. Based on the three-wave technique for molecules sampled in the gas phase [7], one cannot study handedness properties of liquid structures in microwaves, attractive for biological applications. Microwaves are attractive for biological applications because of their sensitivity to water and dielectric contrast. As a ...

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A molecular propeller effect for chiral separation and analysis

Cited by 25 publications

References 33 publications

Mechanical chiral resolution

Mechanical chiral resolution

Phase Enabled Circular Dichroism Reversal in Twisted Bi‐Chiral Propeller Metamolecule Arrays

Microwave chirality discrimination in enantiomeric liquids

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