Abstract:Based on Petri nets as formal language for biomodel engineering, we describe the general concept of a modular modelling approach that considers the functional coupling of modules representing components of the genome, the transcriptome, and the proteome in the form of an executable model. The composable, metadata-containing Petri net modules are organized in a database with version control and accessible through a web interface. The effects of genes and their mutated alleles on downstream components are modell… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.