A modified carbon paste electrode based on Fe3O4@multi-walled carbon nanotubes@polyacrylonitrile nanofibers for determination of imatinib anticancer drug

Ghapanvari, Masoud; Madrakian, Tayyebeh; Afkhami, Abbas; Ghoorchian, Arash

doi:10.1007/s10800-019-01388-x

Cited by 40 publications

(21 citation statements)

References 68 publications

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“…Taking a look in the literature, carbon paste electrodes are modified through various nanomaterials, which usually offer an increased sensitivity. This is due to the increased surface area and fast response rate owing to the enhanced electron-transfer kinetics and reduced resistance [15][16][17]. One class of nanomaterials is metallic nanoparticles, which have attracted great attention due to their variety of applications in fields of biomedical optical and electrical sensing, resulting in the fabrication of many sensors for the detection of various analytes [18,19].…”

Section: Introductionmentioning

confidence: 99%

Influence of Nitrogen-Doped Carbon Dot and Silver Nanoparticle Modified Carbon Paste Electrodes on the Potentiometric Determination of Tobramycin Sulfate: A Comparative Study

et al. 2021

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Two inexpensive and simple methods for synthesis of carbon nanodots were applied and compared to each other, namely a hydrothermal and microwave-assisted method. The synthesized carbon nanodots were characterized using transmission electron microscopy (TEM), ultraviolet-visible (UV-Vis), photoluminescence (PL), Fourier transform-infrared spectroscopy (FTIR), and X-ray diffraction (XRD). The synthesized microwave carbon nanodots had smaller particle size and were thus chosen for better electrochemical performance. Therefore, they were used for our modification process. The proposed electrodes performance characteristics were evaluated according to the IUPAC guidelines, showing linear response in the concentration range 10−6–10−2, 10−7–10−2, and 10−8–10−2 M of tobramycin with a Nernstian slope of 52.60, 58.34, and 57.32 mV/decade for the bare, silver nanoparticle and carbon nanodots modified carbon paste electrodes, respectively. This developed potentiometric method was used for quantification of tobramycin in its co-formulated dosage form and spiked human plasma with good recovery percentages and without interference of the co-formulated drug loteprednol etabonate and excipients.

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Section: Introductionmentioning

confidence: 99%

Influence of Nitrogen-Doped Carbon Dot and Silver Nanoparticle Modified Carbon Paste Electrodes on the Potentiometric Determination of Tobramycin Sulfate: A Comparative Study

et al. 2021

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“…Carbon electrodes, particularly carbon paste electrodes, are extensively used in electrochemical investigations because of their low background current, extensive potential windows, chemical inertness, low cost, fast response, and more environmentally friendly techniques 26 – 29 . Also, they provide suitability for recognizing several organic and biological compounds 30 – 33 . CPE is widely applicable in electroanalysis and electrochemical studies because of its easy fabrication, ease of miniaturization, and simplicity of surface renewal process 34 – 37 .…”

Section: Introductionmentioning

confidence: 99%

Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode

Salim

Ashraf

Hashem

et al. 2022

Sci Rep

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A simple and sensitive voltammetric method was developed and validated for the recognition of the veterinary drug nitroxynil (NTX). The method is based on studying its voltammetric behavior at a carbon paste electrode. Square wave voltammetry (SWV) was successfully applied in this study. The anodic peak current obtained was a linear function of NTX concentration in Britton Robinson buffer of pH 3 over the range of 3.9 × 10–6–1.0 × 10−4 M with lower detection and quantitation limits of 3.1 × 10–7 and 9.4 × 10–7 M, respectively. The proposed method was first applied to the assessment of the drug in commercial vials. The method was further used to monitor the residual amounts of the drug in bovine meat, kidney, fat, and milk samples. The results obtained were favourably compared with those given by reference method. The interference likely to be introduced by co-administered drugs was evaluated. The electrode reaction was elucidated, and electron transfer kinetics were studied.

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“…MNMs consist of either elemental magnetic materials such as iron, cobalt, and nickel or their oxides and mixed oxides. Among magnetic iron oxide nanoparticles, magnetite (Fe 3 O 4 ) and maghemite (γ-Fe 2 O 3 ) have attracted the most attention from various fields with regards to their applicability as drug delivery vehicles, − MRI contrast agents, ,, catalysts, − sensors, − and sorbents. ,− MNMs play a key role in immunoassays because these nanoparticles can be surface-modified with antibodies, oligonucleotides, and aptamers to enable selective binding to target viruses or their biomarkers . Functionalized MNMs can be applied in both the separation and detection steps of the immunomagnetic assay process.…”

Section: Introductionmentioning

confidence: 99%

Magnetic Nanomaterials in Microfluidic Sensors for Virus Detection: A Review

Jalal

Mehrbod

Shojaei

et al. 2021

ACS Appl. Nano Mater.

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Magnetic nanomaterials (MNMs) have gained great interest from different fields of study ranging from wastewater treatment to (bio)sensor development, taking advantage of both nanoscale size (allowing high surface-to-volume ratios) and the opportunity for magnetic manipulation. These materials can be surface-modified with antibodies, oligonucleotides, and aptamers to enable selective binding with target viruses or their biomarkers in biological samples. Using an external magnetic field, MNM-virus/biomarker complexes can be effectively isolated for further analysis. In some cases, the role of MNMs is not limited to simply serve as magnetic sorbents for extraction purposes as they have become an active part of some emerging detection processes (e.g., the use of magnetoresistive sensors). The combined application of MNMs with microfluidics for virus detection provides promising avenues for diagnostic tests that are of lower cost, require less time, and have higher specificity and sensitivity over conventional tests. This review focuses on the different approaches of virus detection using MNMs integrated in microfluidic chips. We will discuss recent research findings and provide insights and future perspectives for the development of low-cost and effective COVID-19 diagnostics tests.

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A modified carbon paste electrode based on Fe3O4@multi-walled carbon nanotubes@polyacrylonitrile nanofibers for determination of imatinib anticancer drug

Cited by 40 publications

References 68 publications

Influence of Nitrogen-Doped Carbon Dot and Silver Nanoparticle Modified Carbon Paste Electrodes on the Potentiometric Determination of Tobramycin Sulfate: A Comparative Study

Influence of Nitrogen-Doped Carbon Dot and Silver Nanoparticle Modified Carbon Paste Electrodes on the Potentiometric Determination of Tobramycin Sulfate: A Comparative Study

Voltammetric estimation of residual nitroxynil in food products using carbon paste electrode

Magnetic Nanomaterials in Microfluidic Sensors for Virus Detection: A Review

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