A Modification of the Short Ammonium Chloride Loading Test in Children

Monnens, L.A.H.

doi:10.1159/000180275

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…Acute mean maximum NAE values based on the highest results of several short urine collection periods of 30-60 min were much higher (171-192 mmol/day per 1.73 m 2 ) [10,11,13) than acute mean maximum renal NAE values based on urine collection periods of 6 h and 24 h (98-137 mmol/day per 1.73 m 2 ) [9,12,13] ( Table 2). Assuming an acute maximum renal NAE in 24 h urine of 120 mmol/day per 1.73 m 2 and a usual renal NAE of 55 mmol/day per 1.73 m 2 in children and adolescents consuming a typical affluent Western-type diet, the acute reserve capacity of the kidney to excrete additional hydrogen ions is 54% of acute maximum renal NAE.…”

Section: Discussionmentioning

confidence: 97%

Renal net acid excretion related to body surface area in children and adolescents

Manz¹,

Wentz²

2000

Pediatric Nephrology

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Renal net acid excretion (NAE) was determined in 2307 24-h urine samples from 566 healthy children and adolescents (285 boys, 281 girls; 2.7-18.3 years) participating in the DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed) Study. NAE is presented for 32 different age and sex groups. Before puberty there is an age-dependent increase in absolute values of NAE (mmol/day) and an age-dependent decrease in NAE related to body weight (mmol/kg per day). NAE related to body surface area (mmol/day per 1.73 m2) was independent of age with higher values in boys than in girls. In summary, body surface area is an appropriate adjustment parameter for renal NAE in the age-independent assessment of the renal acid load in German children and adolescents.

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