A Modification of the Hemagglutination Test for Rheumatoid Arthritis.

Heller, George N.; Jacobson, Abraham S.; Kolodny, Maxwell H.

doi:10.3181/00379727-72-17420

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Methods3

Delayed Hypersensitivity Studies1

By Edward C Franklin1

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1958

1979

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Cited by 110 publications

(23 citation statements)

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“…The RF activity of sera and synovial effusions was measured by the slide latex fixation test (LFT, RA test, Hyland Laboratories, Los Angeles, Calif.) and by the sensitized sheep cell agglutination tests (SCAT) (16). The latter was carried out by settling patterns in microtiter plates.…”

Section: Methodsmentioning

confidence: 99%

Rheumatoid factor-producing cells detected by direct hemolytic plaque assay.

Vaughan¹,

Chihara²,

Moore³

et al. 1976

J. Clin. Invest.

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Section: Methodsmentioning

confidence: 99%

Rheumatoid factor-producing cells detected by direct hemolytic plaque assay.

Vaughan¹,

Chihara²,

Moore³

et al. 1976

J. Clin. Invest.

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“…of diphtheria toxoid. Skin reactions, negative at 6 hours, were read at 18 hours for erythema and induration.…”

Section: Delayed Hypersensitivity Studiesmentioning

confidence: 99%

Effect of a gold salt on the immune response

Persellin

Hess

Ziff

1967

Arthritis & Rheumatism

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“…Rheumatoid factor was determined by the Hyland-RA latex slide agglutination test (Hyland Labs, Costa Mesa, California) and the sensitized sheep cell agglutination (SSCA) test, sensitizing with onefourth the basic agglutinating titer of amboceptor (15). C4 determination.…”

Section: Methodsmentioning

confidence: 99%

Increased C1_q binding immune complexes in felty's syndrome

Hurd

Chubick

Jasin

et al. 1979

Arthritis & Rheumatism

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Sera from patients with Felty's syndrome (FS) and rheumatoid arthritis (RA) were examined for the presence of circulating immune complexes (IC) by using the '=I-Clq binding and monoclonal rheumatoid factor (mRF) techniques. Of 15 patients with FS, 9 (60%) had high 'z51-Clq binding as compared to 3 of 26 RA patients (12%). The average Clq binding was significantly higher in the FS patients than in the RA patients without FS. Clq binding in both FS and RA patients was significantly higher than a group of 90 normal controls. In addition, serum C4 levels were significantly lower in the FS patients than in the RA patients. In contrast to these findings, IC levels in FS and RA patients were very similar when measured by the mRF technique. These studies indicate that FS patients have higher levels of complement-fixing IC in their sera than RA patients without FS. These findings raise the possibility that the complement-fixing IC found in these patients may play a role in the pathogenesis of the neutropenia of FS.

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A Modification of the Hemagglutination Test for Rheumatoid Arthritis.

Cited by 110 publications

References 0 publications

Rheumatoid factor-producing cells detected by direct hemolytic plaque assay.

Rheumatoid factor-producing cells detected by direct hemolytic plaque assay.

Effect of a gold salt on the immune response

Increased C1_q binding immune complexes in felty's syndrome

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A Modification of the Hemagglutination Test for Rheumatoid Arthritis.

Cited by 110 publications

References 0 publications

Rheumatoid factor-producing cells detected by direct hemolytic plaque assay.

Rheumatoid factor-producing cells detected by direct hemolytic plaque assay.

Effect of a gold salt on the immune response

Increased C1q binding immune complexes in felty's syndrome

Contact Info

Product

Resources

About

Increased C1_q binding immune complexes in felty's syndrome