A modern review of penile traction monotherapy and combination therapy for the treatment of peyronie’s disease

Bole, Raevti; White, Lindsay A.; Parikh, Niki; Helo, Sevann; Köhler, Tobias; Ziegelmann, Matthew

doi:10.1038/s41443-020-0247-3

Cited by 8 publications

(2 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Across the majority of PTT trials and regardless of the type of device utilized, PTT monotherapy was not found to have any significant adverse effects. 45 Similar to the VED data, the literature on PTT therapy is very heterogeneous regarding types of traction devices used, timing of intervention during acute versus stable phase, and even duration of therapy amongst other patient factors. For these reasons, drawing comparisons and conclusions from these studies is challenging as the data cannot be analyzed using any type of pooled statistical analysis.…”

Section: Vacuum Erection and Penile Traction Therapymentioning

confidence: 74%

Peyronie’s Disease: An Outcomes-Based Guide to Non-Surgical and Novel Treatment Modalities

Reddy¹,

Dai²,

Song³

et al. 2023

RRU

View full text Add to dashboard Cite

The clinical landscape of Peyronie’s disease is everchanging. There has been growing interest in non-invasive therapeutic options that could assist patients with achieving a meaningful reduction in penile curvature without surgical intervention. These therapies are wide-ranging in terms of their mechanisms of action, efficacies, and short- and long-term safety profiles. Recently, an abundance of outcomes literature on longstanding and novel non-surgical treatment modalities has been published. For sexual medicine providers hoping to offer patients the most up-to-date and evidence-based treatments for the management of Peyronie’s disease, it can be challenging to gain a thorough understanding of this body of literature. In this clinical management review, the workup and current theories on the pathophysiology of Peyronie’s disease are reviewed, and the most recent outcomes data on the currently available non-surgical treatment modalities are presented. With an accurate understanding of the current landscape of Peyronie’s disease treatment, sexual health providers will be able to better evaluate and engage in evidence-based shared decision-making with their patients.

show abstract

Section: Vacuum Erection and Penile Traction Therapymentioning

confidence: 74%

Peyronie’s Disease: An Outcomes-Based Guide to Non-Surgical and Novel Treatment Modalities

Reddy¹,

Dai²,

Song³

et al. 2023

RRU

View full text Add to dashboard Cite

show abstract

“…Several studies showed encouraging results on the efficacy and safety of PTT in both the acute and chronic phase of PD, as well as after PD surgery. [6][7][8] The penile splint is a device, generally assembled by the surgeon and applied at the end of the penile surgery, which aims to improve the surgical outcomes. [9][10][11][12][13]…”

Section: Introductionmentioning

confidence: 99%

Penile Implant Surgery Satisfaction Assessment

Manfredi

Fortier

Faix³

et al. 2021

The Journal of Sexual Medicine

View full text Add to dashboard Cite

Background: Some studies showed encouraging results on the efficacy and safety of penile traction therapy (PTT) after Peyronie's disease (PD) surgery. The early traction therapy (ETT) could be an effective and safe approach to minimize penile shortening in patients undergoing PD surgery. Aim:To evaluate the feasibility, efficacy, and safety of a novel penile splint as ETT in PD patients undergoing grafting techniques.Methods: PD patients underwent plaque incision and grafting (PIG) technique, at the end of the procedure a novel penile splint (ETT) was applied to all patient. The device consisted of two 10Ch intubating stylets, self-adapted to each patient, that kept the penis stretched with the aid of nonabsorbable sutures. The total expense for the materials needed to build each penile splint was less than 15 euros. This active traction was maintained for 1-3weeks, then we removed the stitches leaving the device on-site for a passive traction. Within 3-4 weeks from surgery, the penile splint was replaced by a standard penile traction device. Outcomes:The main outcomes evaluated at 6 months included stretched penile length (SPL), penile curvature, International Index of Erectile Function -Erectile Function domain (IIEF-EF), patient satisfaction, and time to first satisfactory sexual intercourse.Results: A total of 46 patients were enrolled. The median preoperative IIEF-EF, penile curvature, and SPL were 27 points, 70 degrees, and 13 cm. The median follow-up was 15 months. The median postoperative IIEF-EF was 25 points (p < 0.001). The median residual penile curvature was 10 degrees (p < 0.001). The median postoperative SPL was 13 cm (p = 0.269). Eight patients (17.4%) lose 1 cm of SPL, no shortening greater than 1 cm was recorded. The median time to first satisfactory sexual intercourse and patient satisfaction score was 6 weeks and 9 points, respectively.Clinical Implications: Our results could pave the way for a new line of research, which in turn could lead to an improvement in the postoperative management of the patient undergoing surgery for PD.Strength & Limitations: This is the first study evaluating the ETT after PD surgery. The main limitation of this study is the lack of a randomized control group. Other weaknesses are the small sample size and the short follow-up time. Conclusion:Our novel penile splint is inexpensive, easy to assemble, and adaptable to the patient. ETT using this novel device, followed by standard traction therapy, seems to be feasible, effective, and safe.

show abstract