A modern approach to the comprehensive treatment of allergic rhinitis

Abstract

The problem of allergic rhinosinusopathies is one of the most pressing in modern rhinology. It has drawn the attention of clinicians for several decades. Allergic rhinitis is a common disease, the onset of which often come in early childhood. In later life, this disease significantly reduces the quality of life. The widespread prevalence of allergic rhinitis among children and able-bodied adults, growing incidence rates of the disease represent a significant medical and social problem. Allergic rhinitis should be treated by otorhinolaryngologists and allergists-immunologists. Given the pathogenetic mechanisms of the disease, it is necessary to act upon the local symptoms and total body. Extension of disease remissions, teaching patients the principles of elimination therapy and how to maintain a healthy microclimate at home, relapse prevention are the main directions in the treatment of allergic rhinitis. The primary task of otorhinolaryngologists and allergists-immunologists is to restore unlabored nasal breathing in such patients. Symptomatic therapy includes administration of vasoconstrictor drugs, anticholinergics, cromons, local and systemic antihistamines, leukotriene receptor blockers, topical and systemic glucocorticosteroids (GCS), sorbents, pre- and probiotics. Despite the fact that the symptomatic therapy methods cannot provide a long-lasting effect after cancellation, local symptomatic treatment of allergic rhinitis using topical corticosteroids is generally accepted and widely used in the otorhinolaryngology practice. Flixonase is one of the topical corticosteroids that are often prescribed for allergic rhinitis. The aim of our paper was to evaluate the effectiveness of the treatment regimen of allergic rhinitis using Flixonase as a local GCS. 24 people with perennial allergic rhinitis aged from 19 to 38 years were under our observation. The following therapy was prescribed to the patients: decongestants, rinsing the nasal cavity with saline (saltwater) solutions, corticosteroids (Flixonase), mild sedatives. Flixonase showed its efficacy in our study.

Features of course of year-round allergic rhinitis against the background of respiratory intracellular infection

“…Rossiiskaya otorinolaringologiya. 2021;20(3):86-93. https:// doi.org/10.18692/1810-4800-2021-3-86-93 Как известно, аллергический ринит (АР), привлекающий внимание врачей-клиницистов, представляет всемирную социально-экономическую проблему и входит в число наиболее актуальных вопросов современной ринологии [1][2][3][4][5]. По данным P.-J.…”

“…Аллергический ринит (АР) -IgE -опосредованное воспаление слизистой оболочки полости носа, интермитирующего либо персистирующего характера, возникающее в результате иммунной реакции на ингаляционные аллергены у сенсибилизированных лиц [2,11,[17][18][19].…”