A model to investigate the optimal seeder-to-naïve ratio for successful natural Mycoplasma hyopneumoniae gilt exposure prior to entering the breeding herd

Roos, Luiza R.; Fano, Eduardo; Homwong, Nitipong; Payne, Brian; Pieters, Maria

doi:10.1016/j.vetmic.2016.01.008

Cited by 35 publications

(24 citation statements)

References 21 publications

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“…The influence of the lactation period duration in piglet colonization is evidenced by the successful application of segregated early weaning (SEW) to obtain M. hyopneumoniae-free pigs born to positive dams (Alexander, Thornton, Boon, Lysons, & Gush, 1980). Research data have shown that transmission of M. hyopneumoniae among pen-mates is slow (Meyns et al, 2004;Roos, Fano, Homwong, Payne, & Pieters, 2016;Villarreal et al, 2011b), fitting the picture that disease presentation can be the result of early group colonization and subsequent transmission events. However, a clear understanding of M. hyopneumoniae transmission in the field is still needed to improve infection models used in experimental research.…”

Section: Epid Emiologymentioning

confidence: 95%

“…Mycoplasma hyopneumoniae is excreted from the respiratory tract of infected individuals through exhalation of microscopic droplets during coughing episodes and/or by nose‐to‐nose direct contact (Hermann, Brockmeier, Yoon, & Zimmerman, ). M. hyopneumoniae DNA has also been detected in different samples from the oral cavity such as oropharyngeal swabs (Fablet, Marois, Kobisch, Madec, & Rose, ; Hermann et al., ), oral fluids (Roos et al., ) and tonsillar samples (Fablet et al., ; Sibila et al., ).…”

Section: Incubation Period and Kinetic Patternmentioning

confidence: 99%

“…M. hyopneumoniae DNA has also been detected in different samples from the oral cavity such as oropharyngeal swabs (Fablet, Marois, Kobisch, Madec, & Rose, 2010;Hermann et al, 2008), oral fluids (Roos et al, 2016) and tonsillar samples Sibila et al, 2007).…”

Section: Patte Rnmentioning

confidence: 99%

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Update onMycoplasma hyopneumoniaeinfections in pigs: Knowledge gaps for improved disease control

Maes

Sibila

Kuhnert

et al. 2017

Transbound Emerg Dis

199

229

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SummaryMycoplasma hyopneumoniae (M. hyopneumoniae) is the primary pathogen of enzootic pneumonia, a chronic respiratory disease in pigs. Infections occur worldwide and cause major economic losses to the pig industry. The present paper reviews the current knowledge on M. hyopneumoniae infections, with emphasis on identification and analysis of knowledge gaps for optimizing control of the disease. Close contact between infected and susceptible pigs is the main route of M. hyopneumoniae transmission. Management and housing conditions predisposing for infection or disease are known, but further research is needed to better understand M. hyopneumoniae transmission patterns in modern pig production systems, and to assess the impor-

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Section: Epid Emiologymentioning

confidence: 95%

Section: Incubation Period and Kinetic Patternmentioning

confidence: 99%

See 1 more Smart Citation

Update onMycoplasma hyopneumoniaeinfections in pigs: Knowledge gaps for improved disease control

Maes

Sibila

Kuhnert

et al. 2017

Transbound Emerg Dis

199

229

View full text Add to dashboard Cite

show abstract

“…M. hyopneumoniae is recognized as an important pathogen contributing to respiratory disease and unthriftiness in pigs [12, 13]. The combined impacts of M. hyopneumoniae on respiratory disease and impaired growth have led to the recent development and adoption of methods to eliminate this pathogen from large swine herds through the use of breeding management combined with antibiotic therapy [14, 15]. If the effects of M. ovipneumoniae on lamb growth and productivity are similar to those of M. hyopneumoniae in swine, similar efforts at flock-level elimination of this pathogen may be merited.…”

Section: Introductionmentioning

confidence: 99%

A pilot study of the effects of Mycoplasma ovipneumoniae exposure on domestic lamb growth and performance

Besser

Levy

Ackerman

et al. 2018

Preprint

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Mycoplasma ovipneumoniae is a globally distributed pathogen that has been associated with pneumonia in both domestic and wild Caprinae. It is closely related to M. hyopneumoniae, a respiratory pathogen of swine that is associated with decreased growth rates of pigs as well as clinical respiratory disease. In order to assess the effects of M. ovipneumoniae on lamb performance, we generated a cohort of lambs free of M. ovipneumoniae by segregation of test negative ewes after lambing, then compared the growth and carcass quality traits of M. ovipneumoniae-free and -colonized lambs from weaning to harvest. Some signs of respiratory disease were observed during the feeding trial in both lamb groups, but the M. ovipneumoniae-exposed group included more affected lambs and higher average disease scores. At harvest, lungs of lambs in both groups showed few grossly visible lesions, although the M. ovipneumoniae-exposed group did exhibit increased microscopic lung lesions (P<0.05). In addition, M. ovipneumoniae exposed lambs produced lower average daily gains (P<0.05), and lower yield grade carcasses (P<0.05) compared to those of non-exposed lambs. The results demonstrated the feasibility of test and segregation for elimination of M. ovipneumoniae from groups of sheep and suggested that this pathogen may impair lamb growth and productivity even in the absence of overt respiratory disease.

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“…In addition, optimised PCR conditions have been developed for specific respiratory pathogens including PRRSV [22, 23], SIV [24, 25] and PCV2 [26, 27]. Most focus has been on viral rather than bacterial pathogen detection in OF but the knowledge base is increasing for Actinobacillus pleuropneumoniae , Haemophilus parasuis [28] and M. hyo [29–31]. In addition, the OF platform relies on a pooled sample at pen-level from animals that may or may not interact individually with the sampling rope and may themselves be shedding pathogen, or have antibody titres, at differing levels thereby raising potential constraints related to sensitivity of the test.…”

Section: Introductionmentioning

confidence: 99%

The use of oral fluids to monitor key pathogens in porcine respiratory disease complex

et al. 2017

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BackgroundThe usefulness of oral fluid (OF) sampling for surveillance of infections in pig populations is already accepted but its value as a tool to support investigations of porcine respiratory disease complex (PRDC) has been less well studied. This study set out to describe detection patterns of porcine reproductive and respiratory syndrome virus (PRRSV), porcine circovirus type 2 (PCV2), swine influenza virus type A (SIV) and Mycoplasma hyopneumoniae (M. hyo) among farms showing differing severity of PRDC.The study included six wean-to-finish pig batches from farms with historical occurrence of respiratory disease. OF samples were collected from six pens every two weeks from the 5th to the 21st week of age and tested by real time PCR for presence of PRRSV, SIV and M. hyo and by quantitative real time PCR for PCV2. Data was evaluated alongside clinical and post-mortem observations, mortality rate, slaughter pathology, histopathology, and immunohistochemistry testing data for PCV2 antigen where available.ResultsPRRSV and M. hyo were detectable in OF but with inconsistency between pens at the same sampling time and within pens over sequential sampling times. Detection of SIV in clinical and subclinical cases showed good consistency between pens at the same sampling time point with detection possible for periods of 2–4 weeks. Quantitative testing of OF for PCV2 indicated different patterns and levels of detection between farms unaffected or affected by porcine circovirus diseases (PCVD). There was good correlation of PCR results for multiple samples collected from the same pen but no associations were found between prevalence of positive test results and pen location in the building or sex of pigs.ConclusionsDetection patterns for PRRSV, SIV and M. hyo supported the effectiveness of OF testing as an additional tool for diagnostic investigation of PRDC but emphasised the importance of sampling from multiple pens and on multiple occasions. Preliminary evidence supported the measurement of PCV2 load in pooled OF as a tool for prediction of clinical or subclinical PCVD at farm level.

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A model to investigate the optimal seeder-to-naïve ratio for successful natural Mycoplasma hyopneumoniae gilt exposure prior to entering the breeding herd

Cited by 35 publications

References 21 publications

Update onMycoplasma hyopneumoniaeinfections in pigs: Knowledge gaps for improved disease control

Update onMycoplasma hyopneumoniaeinfections in pigs: Knowledge gaps for improved disease control

A pilot study of the effects of Mycoplasma ovipneumoniae exposure on domestic lamb growth and performance

The use of oral fluids to monitor key pathogens in porcine respiratory disease complex

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