A model-based optimization of microalgal cultivation strategies for lipid production under photoautotrophic condition

Ryu, Keun-Ho; Kim, Boeun; Lee, Jay H.

doi:10.1016/j.compchemeng.2018.10.004

Cited by 30 publications

(11 citation statements)

References 53 publications

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“…To overcome the cost problem, extensive research efforts have been devoted to the improvement of the available technologies as well as the development of new ones. Until now, such studies have mostly focused on comparing and improving the economics of different cultivation methods (e.g., open pond system and various photobioreactors) through rigorous techno-economic analyses − and using mathematical models and dynamic optimization techniques. − On the conversion side, however, while many different transesterification (TE) technologies have evolved, comparative techno-economic analyses among the different TE technologies are rather scarce.…”

Section: Introductionmentioning

confidence: 99%

Comparative Techno-Economic Analysis of Transesterification Technologies for Microalgal Biodiesel Production

Heo

Lee

2019

Ind. Eng. Chem. Res.

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In this paper, three different transesterification technologies, catalytic, enzymatic, and in situ transesterification, are examined and compared for the production of microalgal biodiesel through a comprehensive technoeconomic analysis. Conceptual process designs are proposed, and process models are developed using the commercial software of SuperPro Designer. Base case results showed that the lowest biodiesel production cost is achieved by the catalytic transesterification ($4.77/kg), followed by the in situ ($9.92/kg) and enzymatic transesterification ($12.53/kg). Additionally, a global sensitivity analysis is performed to identify the important parameters and variables with strong influences on the biodiesel production cost. Each process was shown to be sensitive to different factors with the extraction solvent cost for the catalytic transesterification process, and the transesterification reactant alcohol cost for the enzymatic and in situ transesterification processes, respectively, being the most important one. The analysis results presented in this work can provide some guidelines for the future development of microalgal biodiesel production processes implementing the transesterification process.

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Section: Introductionmentioning

confidence: 99%

Comparative Techno-Economic Analysis of Transesterification Technologies for Microalgal Biodiesel Production

Heo

Lee

2019

Ind. Eng. Chem. Res.

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“…As shown in above sections including two examples, the proposed model having a new concept for expressing cell growth behaviors can well describe microalgal growth and target internal products’ behaviors. The proposed model can contribute to improve the performance (e.g., productivity, or production cost) of microalgae cultivation process by using similar model-based way to enhance the performance of cultivation process in previous works. − Furthermore, the proposed model is capable of predicting the behavior of major microalgal components during the cultivation. Finally, it can estimate the economic feasibility of microalgal refinery more reliably since the proposed model can estimate all the byproducts of microalgal biorefinery.…”

Section: Resultsmentioning

confidence: 99%

Mathematical Modeling of Microalgal Internal Metabolic Behaviors under Heterotrophic Conditions and Its Application

Ryu

Kim

Heo

et al. 2019

Ind. Eng. Chem. Res.

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Heterotrophic cultivation can be a preferred option for commercial microalgal biorefinery owing to its significantly higher productivity and lipid content leading to high value products. However, limited modeling works have been carried out on heterotrophic culturing of microalgae so far. In this research, a mathematical model is developed to describe microalgae’s metabolic behavior under heterotrophic conditions with their internal components classified into nine types (nucleotides, amino acids, proteins, polysaccharides, monosaccharides, membrane lipids, neutral lipids, and pigments including carotenoid and chlorine families). The modeling is intended to be general as the objective is to build an overarching model capable of describing microalgal behavior for a wide variety of microalgal species. However, the general model turns out to be nonparsimonious, containing a very large number of parameters, which complicates parameter estimation and optimization in its applications. To assist in applications, a model reduction procedure is suggested and demonstrated using two example cases. Therefore, the result is an overarching general model, which can be tailored to specific types of applications at hand, circumventing the need to develop a new model from scratch for each new type of application. The model can be used to improve the design and operation of a microalgal cultivation process with respect to specific targeted products, thereby contributing to the enhanced economic feasibility and sustainability of microalgal biorefinery.

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“…The key advantage and disadvantage of each mode is described in Table 3. However, among the different cultivation modes, phototrophic cultivation offers slow growth rate and lower biomass productivity due to lesser light availability when cell number and diameter increased due to self-shading [88]. There are more cultivation modes with external organic carbon sources categorized as mixotrophic and heterotrophic cultivation modes.…”

Section: Mode Of Microalgae Cultivationmentioning

confidence: 99%

Integrated Approach for Wastewater Treatment and Biofuel Production in Microalgae Biorefineries

et al. 2021

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The increasing world population generates huge amounts of wastewater as well as large energy demand. Additionally, fossil fuel’s combustion for energy production causes the emission of greenhouse gases (GHG) and other pollutants. Therefore, there is a strong need to find alternative green approaches for wastewater treatment and energy production. Microalgae biorefineries could represent an effective strategy to mitigate the above problems. Microalgae biorefineries are a sustainable alternative to conventional wastewater treatment processes, as they potentially allow wastewater to be treated at lower costs and with lower energy consumption. Furthermore, they provide an effective means to recover valuable compounds for biofuel production or other applications. This review focuses on the current scenario and future prospects of microalgae biorefineries aimed at combining wastewater treatment with biofuel production. First, the different microalgal cultivation systems are examined, and their main characteristics and limitations are discussed. Then, the technologies available for converting the biomass produced during wastewater treatment into biofuel are critically analyzed. Finally, current challenges and research directions for biofuel production and wastewater treatment through this approach are outlined.

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A model-based optimization of microalgal cultivation strategies for lipid production under photoautotrophic condition

Cited by 30 publications

References 53 publications

Comparative Techno-Economic Analysis of Transesterification Technologies for Microalgal Biodiesel Production

Comparative Techno-Economic Analysis of Transesterification Technologies for Microalgal Biodiesel Production

Mathematical Modeling of Microalgal Internal Metabolic Behaviors under Heterotrophic Conditions and Its Application

Integrated Approach for Wastewater Treatment and Biofuel Production in Microalgae Biorefineries

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