Stochastic basis expansions are applied to formulate and solve the problem of including uncertainty in numerical models of acoustic wave propagation within ocean waveguides. As an example, a constrained least-squares approach is used to estimate the intensity of an acoustic field whose waveguide environment has uncertainty in both source depth and sound speed. The mean intensity, a second moment of the field, and its probability distribution are computed and compared with independent Monte-Carlo computations of these quantities. Very good agreement is obtained, indicating the potential of stochastic basis expansions for describing multiple sources of uncertainty and their effect on acoustic propagation.