A mixed model approach to estimate the survivor average causal effect in cluster‐randomized trials
Wei Wang,
Guangyu Tong,
Shashivadan P. Hirani
et al.
Abstract:In many medical studies, the outcome measure (such as quality of life, QOL) for some study participants becomes informatively truncated (censored, missing, or unobserved) due to death or other forms of dropout, creating a nonignorable missing data problem. In such cases, the use of a composite outcome or imputation methods that fill in unmeasurable QOL values for those who died rely on strong and untestable assumptions and may be conceptually unappealing to certain stakeholders when estimating a treatment effe… Show more
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