A mitochondria-targeted dual-reactable fluorescent probe for fast detection of H2S in living cells

A highly sensitive and selective fluorescent probe for tracking hydrogen sulfide in red wine

“…Besides, the limit of detection (LOD) of LODNBS for H 2 S was calculated to be 72 nM by the 3σ method (LOD=3σ/K), which is much lower than the concentration of physiological H 2 S in human blood (35–80 μM), [34] suggesting that LODNBS can detect H 2 S with high sensitivity. Furthermore, according to the comparison of LODNBS with other reported fluorescent probes in the literature (Table 1), the LOD of LODNBS for H 2 S was lower than other published probes [35–40] . The time dependent fluorescence spectra of LODNBS (20 μM) to H 2 S (100 μM) were then conducted.…”

Reaction-Based Luminescent Probes for Reactive Sulfur, Oxygen, and Nitrogen Species: Analytical Techniques and Recent Progress

“…Hydrogen sulfide has sparked vast creativity in the design of reaction-based triggers for this reactive analyte, and these can be generally categorized into reduction-based triggers, electrophilic triggers, copper-based triggers, and a few other interesting developments, including triggers incorporating molecular recognition (Figures – ). Reduction-based triggers include azides, − sulfonyl azides, , nitro groups, − nitroso groups, and quinones . A wide variety of electrophilic triggers that operate via hydrogen sulfide’s nucleophilicity have been developed including aldehyde-assisted ester cleavage, aldehyde-assisted conjugate addition, aldehyde-assisted dinitrophenyl cleavage, nucleophilic aromatic substitution, , nucleophilic addition to an imine, , nitrobenzoxadiazole with amine ,− or alcohol , leaving groups, vinyl chloride substitution alone or followed by cyclization, an aryl cyanate, disulfide-assisted ester cleavage, − diselenide-assisted ester cleavage,…”

A Highly Selective and Sensitive Colorimetric Chemosensor for the Detection of Hydrogen Sulfide: A Real‐time Application in Multiple platforms

“…In recent years, with the ongoing efforts of research groups, various methods have been developed to detect H 2 S. For example, electrochemical assays (10–14), chromatography (15–17), metal‐induced sulfide precipitation (18) and optical probes are the main techniques to detect H 2 S. Among these methods, optical detection has received significant attention in recent years owing to its simplicity, high sensitivity and selectivity, and good repeatability (19–38). Chemodosimeter is the most common optical approach in which the chemical probe is incorporated with an H 2 S selective irreversible responsive unit and optical response modulator.…”