Abstract:Dear Editor:Neoplasms of the anal canal are extremely rare, accounting for about 1 % of all gastrointestinal tumors and less than 5 % of anorectal malignancies. According to the latest WHO classification, growths in the anal canal can be broadly categorized into epithelial, mesenchymal, and secondary tumors. Squamous cell carcinoma (SCC) and adenocarcinoma of the anal canal (ACC) both arise from the epithelium; however, while SCCs represent the majority of epithelial anal cancers at 80 %, adenocarcinomas make … Show more
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