A mild method for regioselective de-O-methylation of saccharides by Co2(CO)8/Et3SiH/CO system

Synthesis of carbohydrate building blocksviaregioselective uniform protection/deprotection strategies

“…A similar protocol was applied to the regioselective removal of methyl ether protecting groups. 99 For per- O -methylated thioglucoside, primary methyl group was removed selectively and the respective 6- O -acetyl product was formed in 52% yield along with 3,6-di -O -acetyl compound was also formed as a minor side-product.…”