A microscale photovoltaic neurostimulator for fiber optic delivery of functional electrical stimulation

Song, Yoon‐Kyu; Stein, John; Patterson, William R.; Bull, Christopher; Davitt, Kristina; Serruya, Mijail; Zhang, Jiayi; Nurmikko, A. V.; Donoghue, John P.

doi:10.1088/1741-2560/4/3/006

Cited by 20 publications

(18 citation statements)

References 12 publications

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“…To power the 16-channel neural recording device by IR light, we built PPSs from a custom designed GaAs/AlGaAs multilayer, multi-junction epitaxially-grown tandem structure as previously described [12,13]. However, in this work, we maximized the power conversion efficiency further by employing large optical apertures for the incident…”

Section: A Fabrication Of the Photovoltaic Power Supply (Pps)mentioning

confidence: 99%

A fiber optic multi-channel neural recording system for freely moving rats

Park

Ozden

Song

et al. 2013

2013 6th International IEEE/EMBS Conference on Neural Engineering (NER)

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Future brain-computer interfaces will benefit from technologies that enable efficient, reliable and high-speed transmission of multichannel neural data. As one approach, we present a miniature multichannel neural recording device that utilizes infrared (IR) fiber optics for dual purpose of powering active electronic circuits in the compact head-mounted module and extracting of broadband multichannel neural data. We demonstrate the microsystem's chronic performance in awake, behaving rats with intracortical neural sensors. In a prototype for small animal model, the microelectronic device architecture consisted of (i) an implantable 'front-end' carrying an ultra-low power 16-channel preamplifier and a multiplexer chip integrated directly onto a 4x4 cortical microelectrode array to access neural activity, and (ii) an ultra-light 'back-end' housing an analog-to-digital converter, a low power digital controller chip, an IR photovoltaic device and an IR microlaser, the latter to convert multiplexed multichannel neural data to a stream of IR pulses. The implanted device was able to monitor motor cortical activity in rats during free behavior for more than a month without degradation of device performance.

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Section: A Fabrication Of the Photovoltaic Power Supply (Pps)mentioning

confidence: 99%

A fiber optic multi-channel neural recording system for freely moving rats

Park

Ozden

Song

et al. 2013

2013 6th International IEEE/EMBS Conference on Neural Engineering (NER)

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“…On the flip side of the substrate is a planar RF receiving coil for enabling inductively coupled (transcutaneous) receiving of power and clock to the microsystem. (We note that both power and clocking can also be configured to be delivered optically via an optical fiber using a high-efficiency photovoltaic energy converter [54]. ) The breakdown of the total system power budget at this writing is shown in Table 1.…”

Section: Fully Implantable Wireless Neural Microsystems—aiming Formentioning

confidence: 99%

Listening to Brain Microcircuits for Interfacing With External World—Progress in Wireless Implantable Microelectronic Neuroengineering Devices

et al. 2010

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Acquiring neural signals at high spatial and temporal resolution directly from brain microcircuits and decoding their activity to interpret commands and/or prior planning activity, such as motion of an arm or a leg, is a prime goal of modern neurotechnology. Its practical aims include assistive devices for subjects whose normal neural information pathways are not functioning due to physical damage or disease. On the fundamental side, researchers are striving to decipher the code of multiple neural microcircuits which collectively make up nature’s amazing computing machine, the brain. By implanting biocompatible neural sensor probes directly into the brain, in the form of microelectrode arrays, it is now possible to extract information from interacting populations of neural cells with spatial and temporal resolution at the single cell level. With parallel advances in application of statistical and mathematical techniques tools for deciphering the neural code, extracted populations or correlated neurons, significant understanding has been achieved of those brain commands that control, e.g., the motion of an arm in a primate (monkey or a human subject). These developments are accelerating the work on neural prosthetics where brain derived signals may be employed to bypass, e.g., an injured spinal cord. One key element in achieving the goals for practical and versatile neural prostheses is the development of fully implantable wireless microelectronic “brain-interfaces” within the body, a point of special emphasis of this paper.

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“…The high efficiency GaAs neurostimulator [8] did this through a heterogeneous tandem cell structure. Using bulk silicon processes allows for the inclusion of MOSFETs and integrated capacitors which make it possible to integrate the electronics to enable a microdevice such as a Smart FLAMES.…”

Section: Photodiodesmentioning

confidence: 99%

“…Fiber guided high-efficiency III-V heterojunction photovoltaic stimulators have been used for neurostimulation [8]. Retinal photovoltaic arrays [9] Manuscript received March 7, 2011 Fig.…”

Section: Introductionmentioning

confidence: 99%

Addressable floating light activated micro-electrical stimulators for wireless neurostimulation

Freedman

Spuhler

Cevik

et al. 2011

2011 5th International IEEE/EMBS Conference on Neural Engineering

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Abstract-Stimulation of the central nervous system can be useful for treating neurological disorders. Wireless neurostimulating devices have the benefit that they can float in tissue and do not experience the sheering caused by tethering tension that non-wireless stimulators impose on connecting wires. An optically powered, logic controlled, CMOS microdevice that can decode telemetry data from an optical packet is a potential way of implementing wireless, addressable, microstimulators. Through the use of an optical packet, different devices can be addressed for stimulation, allowing spatially selective activation of neural tissue. This work presents the design and simulations of such a neural stimulation device, specifically an optically powered CMOS circuit that decodes telemetry data and determines whether it has been addressed.

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A microscale photovoltaic neurostimulator for fiber optic delivery of functional electrical stimulation

Cited by 20 publications

References 12 publications

A fiber optic multi-channel neural recording system for freely moving rats

A fiber optic multi-channel neural recording system for freely moving rats

Listening to Brain Microcircuits for Interfacing With External World—Progress in Wireless Implantable Microelectronic Neuroengineering Devices

Addressable floating light activated micro-electrical stimulators for wireless neurostimulation

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