A Microneedles Balloon Catheter for Endovascular Drug Delivery (Adv. Mater. Technol. 8/2021)

Moussi, Khalil; Haneef, Ali A.; Alsiary, Rawiah; Diallo, Elhadj M.; Boone, Matthieu; Abu-Araki, Huda; Al‐Radi, Osman O.; Kosel, Jürgen

doi:10.1002/admt.202170046

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…Finally, in the crimping process, the stent is compressed onto the balloon. [4][5][6] The stents and delivery systems that are widely used in patients have been developed based on different perspectives. Particularly, the research and development trend to improve the functionality of the stent (drug deliverability and biodegradability) and delivery system (pushability and trackability) entails making the strut thinner.…”

Section: Introductionmentioning

confidence: 99%

Formation of Balloon with Porous Structures in NaCl Vapor Assisted by Amphiphilic Polymer for Stent Delivery System

Lee,

Park,

Kim

et al. 2023

Adv Materials Technologies

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Recently, bioabsorbable vascular stents (BVSs) are actively studied owing to their ability to dissolve within the human body. However, despite their advantages, BVSs often dislodge from the expandable balloon‐based delivery system when transported to the lesion site. In this study, a novel methodology aiming at increasing the retention force between the stent and the delivery system is presented. The breath‐figure method is adopted to form a porous structure and enhance adhesion. Additionally, numerical and experimental methods are used to evaluate the effect of surface tension between two immiscible fluids (polymeric solutions and droplets). To control the interfacial tension between the solution and droplets, an amphiphilic polymer and NaCl‐added vapor are used. By selecting the appropriate parameters, a sponge‐like structure is prepared on the stent delivery system. To verify its applicability, the two types of structures presented in this study are experimentally compared. These findings provide valuable guidelines for understanding the mechanism of breath‐figure patterns. Thus, the innovative methodology developed in this study demonstrates simplicity and scalability for large‐area production, making it potentially applicable to industrial technologies and offering new insights into biomedical engineering.

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Section: Introductionmentioning

confidence: 99%