“…They demonstrated the device application using ibuprofen and generated a detection limit of 10 −8 M. 216 Gril et al presented a fluorescence-based sensor for detecting dissolved oxygen in water. The system is composed of silica capillaries and optical fibers, and upon testing, revealed an accuracy of 0.025 mg L −1 with a response time of less than 60 s. 217 Finally, Charles et al demonstrated a bifurcated 128-microchannel device for environmental monitoring of explosives. The device, constructed of PMMA, used fluorescence-based displacement immunoassay for explosive determination.…”