A microbiological study of neonatal conjunctivitis in two hospitals in Tehran, Iran

Afjeiee, Seyed Abolfazl; Tabatabaei, Sedigheh Rafiei; Fallah, Fatemeh; Fard, Arezou Tavakkoly; Shiva, Farideh; Adabian, Saadat; Karimi, Abdollah; Rahbar, Mohammad

doi:10.1016/s2222-1808(13)60096-1

Cited by 7 publications

(14 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…12 In the present study, males and females were equally affected. However, most of the studies have shown male preponderance [13][14][15][16] The male gender as a risk factor for increased neonatal infection has been attributed to Y-gene. 15 The mean age of onset of conjunctivitis was 6.1 days of birth in a study by Khosdel A, et al before 7 days of birth in a study by Mohile M, et al and 3.7 days in a study by Soltanzadeh M H, et al 13,14 In the present study, the mean age of onset of conjunctivitis is 3.6 days of life.…”

Section: Discussionmentioning

confidence: 99%

Culture Positive Cases of Ophthalmia Neonatorum in a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study

2021

View full text Add to dashboard Cite

Introduction: Ophthalmia neonatorum although runs a benign course mostly, sometimes may progress to sight threatening complications. The study was conducted to find the prevalence of culture positive cases of opthalmia neonatorum. Methods: It was a descriptive cross-sectional study conducted at a tertiary care center from January to December 2019. Ethical clearance was obtained from institutional review committee of Kathmandu Medical College. Convenience sampling was done. All data were entered into excel and, then for analysis, exported to Statistal Package for Social Sciences version 21. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: The prevalence of culture positive cases of opthalmia neonaturum is 10 (55.55%) (32.61-78.49 at 95% Confidence Interval). The causative organisms were coagulase negative Staphylococcus 4 (40%), Staphylococcus aureus 3 (30%), Klebsiella 2 (20%) and Pseudomonas 1 (10%). Culture sensitivity of the isolated organisms were different according to the patient even in case of the same organism. Vancomycin 7 ( 70%) was the most sensitive antibiotic followed by Ciprofloxacin 6 (60%), Amikacin 5 (50%) and Cloxacillin 5 (50%) while Azithromycin 1 (10%), Cefixime 1 (10%) and Cotrimoxazole 1 (10%) were the least sensitive. Conclusions: Staphylococcus species was the most common organism isolated from neonates with ophthalmia neonatorum and vancomycin was the most sensitive antibiotic.

show abstract

Section: Discussionmentioning

confidence: 99%

Culture Positive Cases of Ophthalmia Neonatorum in a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study

2021

View full text Add to dashboard Cite

show abstract

“…Conjunctivitis is one of the main causes of redness and discharge of the eyes, and its prevalence varies according to the patients’ gender and age, and different seasons of the year [ 16 ]. To the best of our knowledge, there is little evidence available in Iran about conjunctivitis caused by M. catarrhalis , although some studies have been performed on the bacterial and viral agents that cause the disease [ 17 , 18 ]. We observed a higher occurrence of conjunctivitis in male (65%) when compared to female (35%) patients.…”

Section: Discussionmentioning

confidence: 99%

“…In this study, the results of culture and PCR methods revealed the occurrence rate of 1% for M. catarrhalis in conjunctivitis samples. In a study by Afjeiee et al [ 17 ] from Tehran, Iran, of the 241 neonates with clinical signs of conjunctivitis, the most frequent isolates were coagulase-negative Staphylococci (n = 130, 53.9%), followed by Chlamydia trachomatis (n = 40, 16.6%). They did not detect M. catarrhalis by routine culture method.…”

Section: Discussionmentioning

confidence: 99%

“…In a study by Jyoti et al [ 22 ] from India, the prevalence of M. catarrhalis was reported as 0.4% in conjunctivitis specimens that was lower than this study. In previous reports from various countries of the world, the coagulase-negative Staphylococci and S. aureus were among the most prevalent species isolated from eye infections, including conjunctivitis [ 17 , 19 , 22 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Low prevalence of Moraxella catarrhalis in the patients who suffered from conjunctivitis in the southwest of Iran

et al. 2020

View full text Add to dashboard Cite

Objective Moraxella catarrhalis is a non-motile Gram-negative diplococcus bacterium that contributed to several human infections including conjunctivitis. This study aimed to reveal the prevalence of M. catarrhalis in patients who suffered from conjunctivitis in Ahvaz city, southwest of Iran. Results Out of 100 conjunctiva swab specimens, M. catarrhalis was isolated only from one (1%) conjunctivitis cases using the culture method. This strain was isolated from a 34 years old female patient. Also, the results of the polymerase chain reaction (PCR) were in agreement with the culture method, and the specimen that showed positive culture was also positive for specific gene of M. catarrhalis. The remaining 99 specimens did not show positive results with any of the culture and PCR methods.

show abstract

“…Currently, in different studies on the epidemiology of NC, bacterial agents of the skin flora and the environment (Staphylococcus sp. ), that is, non-gonococcal bacteria, are most the most frequent isolates in conjunctival secretion cultures 2,9,10 .…”

Section: Introductionmentioning

confidence: 99%

Microbial etiology of neonatal conjunctivitis in a hospital in the city of Medellín

Gaviria-Bravo¹,

Llano-Naranjo²,

Villada-Ochoa³

2020

RMOE

View full text Add to dashboard Cite

We reviewed the medical records of patients diagnosed with neonatal bacterial conjunctivitis with positive cultures of conjunctival secretion. Sociodemographic variables of the mother and the neonate, associated risk factors, results of the microbiological isolations, topical and systemic antibiotic therapy and antibiotic sensitivity were recorded. Results: A total of 69 newborns were identified, 65.22% were male, the average age was 15.7 ± 8.3 days. Major etiological agents identified were Staphylococcus epidermidis (n = 20, 28.9%), Staphylococcus aureus (n = 12, 17.3%) and Haemophilus influenzae (9 patients, 13.0%). There were no positive isolates for Chlamydia trachomatis or Neisseria gonorrhoeae. The most common maternal peripartum risk factors were premature rupture of the ovular membranes (n = 16, 21.33%), urinary tract infection (7 cases, 10.1%), preterm birth syndrome (n = 6, 8.00%) and bacterial vaginosis (5 cases, 7.25%). Resistance to oxacillin 26% (n = 18) and tetracyclines 15% (n = 11) was observed in patients with Staphylococcus infection. Conclusion: Over the years, the epidemiology of neonatal conjunctivitis has changed. Nowadays, gonococcal pathogens are not the most common cause of neonatal conjunctivitis. A significant number of patients with methicillin-resistant S. aureus were observed.

show abstract

A microbiological study of neonatal conjunctivitis in two hospitals in Tehran, Iran

Cited by 7 publications

References 8 publications

Culture Positive Cases of Ophthalmia Neonatorum in a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study

Culture Positive Cases of Ophthalmia Neonatorum in a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study

Low prevalence of Moraxella catarrhalis in the patients who suffered from conjunctivitis in the southwest of Iran

Microbial etiology of neonatal conjunctivitis in a hospital in the city of Medellín

Contact Info

Product

Resources

About