A methodology for developing anisotropic AAA phantoms via additive manufacturing

Galarreta, Sergio Ruiz de; Antón, Raúl; Cazón, Aitor; Finol, Ender A.

doi:10.1016/j.jbiomech.2017.04.001

Cited by 9 publications

(3 citation statements)

References 24 publications

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“…There has been a recent study [ 20 ] on using anisotropic arterial walls by multimaterial 3D printing. Another study [ 18 ] outlined a tunable wall compliance system for the aorta.…”

Section: Discussionmentioning

confidence: 99%

“…Boersen et al [15] studied flow dynamics in EVAR of AAA and presented flow patterns for different endograft designs. Others [16][17][18][19][20][21] concentrated on developing patient-specific phantoms for optical flow measurements. Geoghegan et al [22] described the use of the investment casting method for producing MRI and computed tomography (CT)-based phantoms for flow visualization.…”

Section: Introductionmentioning

confidence: 99%

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Integrated particle image velocimetry and fluid–structure interaction analysis for patient-specific abdominal aortic aneurysm studies

Özcan,

Kocatürk,

Işlak

et al. 2023

BioMed Eng OnLine

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Background Understanding the hemodynamics of an abdominal aortic aneurysm (AAA) is crucial for risk assessment and treatment planning. This study introduces a low-cost, patient-specific in vitro AAA model to investigate hemodynamics using particle image velocimetry (PIV) and flow-simulating circuit, validated through fluid–structure interaction (FSI) simulations. Methods In this study, 3D printing was employed to manufacture a flexible patient-specific AAA phantom using a lost-core casting technique. A pulsatile flow circuit was constructed using off-the-shelf components. A particle image velocimetry (PIV) setup was built using an affordable laser source and global shutter camera, and finally, the flow field inside the AAA was analyzed using open-source software. Fluid–structure interaction (FSI) simulations were performed to enhance our understanding of the flow field, and the results were validated by PIV analysis. Both steady-state and transient flow conditions were investigated. Results Our experimental setup replicated physiological conditions, analyzing arterial wall deformations and flow characteristics within the aneurysm. Under constant flow, peak wall deformations and flow velocities showed deviations within − 12% to + 27% and − 7% to + 5%, respectively, compared to FSI simulations. Pulsatile flow conditions further demonstrated a strong correlation (Pearson coefficient 0.85) in flow velocities and vectors throughout the cardiac cycle. Transient phenomena, particularly the formation and progression of vortex structures during systole, were consistently depicted between experimental and numerical models. Conclusions By bridging high-fidelity experimental observations with comprehensive computational analyses, this study underscores the potential of integrated methodologies in enhancing our understanding of AAA pathophysiology. The convergence of realistic AAA phantoms, precise PIV measurements at affordable cost point, and validated FSI models heralds a new paradigm in vascular research, with significant implications for personalized medicine and bioengineering innovations.

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“…There has been a recent study [ 20 ] on using anisotropic arterial walls by multimaterial 3D printing. Another study [ 18 ] outlined a tunable wall compliance system for the aorta.…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Integrated particle image velocimetry and fluid–structure interaction analysis for patient-specific abdominal aortic aneurysm studies

Özcan,

Kocatürk,

Işlak

et al. 2023

BioMed Eng OnLine

View full text Add to dashboard Cite

show abstract

“…The majority reported transparent or translucent materials to create phantoms 5,6,10,11,[14][15][16][17][18][20][21][22][23][24][25][26][28][29][30] and were in agreement that a flexible, transparent model would be of greatest utility, with current levels of technology posing a limitation with regards to accessibility and cost. Some achieved a flexible, transparent model by silicone casting via a 3D printed negative cast of the AAA model, a time-consuming process.…”

Section: D Printing Workflowmentioning

confidence: 99%

Utility of 3D printed abdominal aortic aneurysm phantoms: a systematic review

Coles‐Black

Bolton

Robinson

et al. 2021

ANZ Journal of Surgery

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Background: 3D printed (3DP) abdominal aortic aneurysm (AAA) phantoms are emerging in the literature as an adjunct for the visualization of complex anatomy, particularly for presurgical device selection and simulation. This is the first systematic review to provide a comprehensive overview of 3DP for endovascular aneurysm repair (EVAR) planning and intervention, evaluating the readiness of current levels of technology for mainstream implementation. Methods: A systematic literature search of PubMed and MEDLINE was performed as per PRISMA guidelines using the terms '3D Printing', 'AAA' OR 'EVAR' and related index terms, and further relevant articles were appraised via a snowballing approach. Our last search was conducted on 14 November 2020. Results: Twenty-five articles were identified for critical analysis, with 14 cases or technical reports. Nineteen publications utilized 3DP AAA phantoms to aid presurgical decision making, device selection and design. Four publications explored the utility of 3DP phantoms as EVAR trainers, and one publication examined the technology as a tool for patient education. Flexible, transparent phantoms were deemed most useful; however, the cost and availability of higher end machines limited accessibility. Conclusion: 3DP phantoms have been used in EVAR to facilitate visualization of complex patient anatomy, appropriate device selection, in predicting navigational difficulties and the shape and position of endograft after deployment. These phantoms show promise in reducing known complications such as endoleak, stent graft occlusion and migration; however, larger scale prospective studies are required to validate its impacts on patient outcomes and cost savings to the healthcare system.

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Principles of three-dimensional printing and clinical applications within the abdomen and pelvis

et al. 2018

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Improvements in technology and reduction in costs have led to widespread interest in three-dimensional (3D) printing. 3D-printed anatomical models contribute to personalized medicine, surgical planning, and education across medical specialties, and these models are rapidly changing the landscape of clinical practice. A physical object that can be held in one's hands allows for significant advantages over standard two-dimensional (2D) or even 3D computer-based virtual models. Radiologists have the potential to play a significant role as consultants and educators across all specialties by providing 3D-printed models that enhance clinical care. This article reviews the basics of 3D printing, including how models are created from imaging data, clinical applications of 3D printing within the abdomen and pelvis, implications for education and training, limitations, and future directions.

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A methodology for developing anisotropic AAA phantoms via additive manufacturing

Cited by 9 publications

References 24 publications

Integrated particle image velocimetry and fluid–structure interaction analysis for patient-specific abdominal aortic aneurysm studies

Integrated particle image velocimetry and fluid–structure interaction analysis for patient-specific abdominal aortic aneurysm studies

Utility of 3D printed abdominal aortic aneurysm phantoms: a systematic review

Principles of three-dimensional printing and clinical applications within the abdomen and pelvis

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