A Method of Image Analysis for Primary Angle Closure Glaucoma

Kondo, Takehisa; Nakatsu, Ayako; Park, Masami

doi:10.1159/000310594

Cited by 3 publications

(3 citation statements)

References 3 publications

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“…The tears are often small, and 87 % of tears occur in the ora serrata or the nonpigmented epithelium of the pars plana or pars plicata of the ciliary body in Schwartz-Matsuo syndrome [ 8 , 9 ]. The tears of the nonpigmented epithelium of the ciliary body were mostly located in the superotemporal quadrant followed by the inferotemporal and inferonasal quadrants [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

UBM-guided scleral buckling for Schwartz-Matsuo syndrome with tear of nonpigmented epithelium of the ciliary body: a case report

Wang

Jiang

et al. 2021

BMC Ophthalmol

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Background Tears in Schwartz-Matsuo syndrome are generally confirmed by preoperative ophthalmoscopic examination. A case of Schwartz-Matsuo syndrome with a tear detected by ultrasound biomicroscopy (UBM) and treated by UBM-guided scleral buckling was reported, and its mechanism was analysed. Case presentation A 40-year-old Chinese man presented with blurry vision and intermittent eye pain in his left eye for three days. The visual acuity of the left eye decreased from 20/20 to 20/40, and the intraocular pressure (IOP) fluctuated dramatically from 24.0 mmHg to 56.7 mmHg at the first visit. Gonioscopy revealed that the chamber angle remained open. A macula-involving inferior retinal detachment extending from 4:30 to 9:30 with no obvious causative break was observed through ophthalmoscopic examination. However, a single small tear was detected at the nonpigmented epithelium of pars plana of the ciliary body at approximately 7–8 o’clock by UBM. The loss of photoreceptor outer segments and ellipsoid zone and the existence of macular microcysts in the inner and outer nuclear layers were observed in the detached macula by optical coherence tomography. Then, he underwent successful scleral buckling guided by UBM. Three months later, the retina was flat with normal IOP, and the best corrected visual acuity of his left eye gradually improved to 20/25. UBM confirmed the closure of the tear. Conclusions Tear of the nonpigmented epithelium of the ciliary body is a rare condition associated with Schwartz-Matsuo syndrome. UBM plays a key role in detecting occult tears of the nonpigmented epithelium of the ciliary body, guiding scleral buckling surgery, and observing the closure of the tear postoperatively.

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Section: Discussionmentioning

confidence: 99%

UBM-guided scleral buckling for Schwartz-Matsuo syndrome with tear of nonpigmented epithelium of the ciliary body: a case report

Wang

Jiang

et al. 2021

BMC Ophthalmol

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“…[19][20][21] Various substances like growth factors, fibronectin, and so on are released into the aqueous humour after the surgery due to the breakdown of blood aqueous humour, which facilitates the proliferation and differentiation of the adhered LECs. [22][23][24] It would be worthwhile to further investigate the role of these live LECs in the incidence and severity of PCO. Our study may have clinical relevance in the context of both ACO and PCO.…”

Section: Discussionmentioning

confidence: 99%

Confirmation of the presence of lens epithelial cells in the anterior chamber after phacoemulsification

Vasavada

Johar

Praveen

et al. 2008

Eye

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Aims To detect the presence of lens epithelial cells in the anterior chamber of the eye at the end of phacoemulsification. Methods A prospective observational study was carried out on 50 patients undergoing phacoemulsification. Fluid from the anterior chamber was collected from these patients at the end of phacoemulsification. Thirty samples were processed for detection of viability using calcein AM-propidium iodide. Remaining samples were processed for immunofluorescence detection of aA-crystallin and vimentin. The nonparametric Mann-Whitney U test was applied.Results The presence of lens epithelial cells was confirmed in 27 of the first 30 samples. The total number of cells observed in these 27 samples were 64.70 ± 58.49. Within these 27 samples, 35.5% were live cells and 64.5% were dead. The cells were present as single cell or in groups. Twenty three percentage samples were also positive for nucleated lens fibres. In the remaining 20 samples, 89% cells were confirmed to be lens epithelial cells. Conclusions We show for the first time, the presence of cells in the fluid of the anterior chamber at the end of phacoemulsification. The cells were positive for aA-crystallin and vimentin, thereby suggesting that they were lens epithelial cells.

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“…Although there are several studies of quantitative ACD measurement, [10][11][12][13][14][15] their clinical usefulness is not consistent. The instruments or methods employed are expensive and difficult to handle, require complicated quantitative analysis, and have low reproducibility.…”

Section: Discussionmentioning

confidence: 99%

Finding cases of angle-closure glaucoma in clinic setting using a newly developed instrument

Kashiwagi

Kashiwagi²,

Hiejima

et al. 2005

Eye

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Purpose To validate the applicability of a newly developed, noncontact scanning peripheral anterior chamber depth analyzer (SPAC) for screening eyes at the risk of angleclosure glaucoma (ACG). Subjects and methods All glaucoma patients who visited the University of Yamanashi Hospital from February through May 2003 were enrolled, except those with aphakic eye or pseudophakic eye. Of the 552 enrolled patients, 48 with ACG or narrow angles requiring laser iridotomy (LI) were categorized as patients with high-risk ACG eyes, and those with open angle were categorized as patients with control eyes. In all, 20 patients with ACG or narrow angles requiring prophylactic LI, who were followed up by an independent private ophthalmic clinic, were enrolled for threshold analysis. Nonophthalmologists measured anterior chamber depth and the averaged values of three measurements were employed for analysis. Threshold analysis and discriminant analysis were employed for determining the sensitivity and specificity of SPAC for diagnosing eyes with high-risk ACG. Results SPAC distinguished well the highrisk ACG eyes from the control eyes, and one of the most useful criteria for screening is as follows: any of the four measured points should exceed 95% confidence interval, and sensitivity and specificity should be 97.6 and 83.5%, respectively. Conclusion SPAC is thought to be useful for detecting eyes at the risk of ACG by nonophthalmologists.

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A Method of Image Analysis for Primary Angle Closure Glaucoma

Cited by 3 publications

References 3 publications

UBM-guided scleral buckling for Schwartz-Matsuo syndrome with tear of nonpigmented epithelium of the ciliary body: a case report

UBM-guided scleral buckling for Schwartz-Matsuo syndrome with tear of nonpigmented epithelium of the ciliary body: a case report

Confirmation of the presence of lens epithelial cells in the anterior chamber after phacoemulsification

Finding cases of angle-closure glaucoma in clinic setting using a newly developed instrument

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