A Method for the Removal of Tungsten Carbide Rings

Allen, Keith; Rizzo, Marco; Sadosty, Annie T.

doi:10.1016/j.jemermed.2011.07.032

Cited by 15 publications

(12 citation statements)

References 7 publications

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“…It is easy to cut soft materials such as copper, gold, silver, plastic [7]. Breaking the rings made of hard alloys such as ceramic and tungsten carbide is easier than cutting them [8]. However, it is necessary to use electric power saws to cut the rings made of very hard alloys such as titanium and steel.…”

Section: Case Reportmentioning

confidence: 99%

Removing the ring stuck on finger with a high speed motor: a case report

Ceylan¹

2019

Ann Clin Anal Med

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A considerable number of patients apply to the emergency departments with rings, made of different alloys and in different shapes, stuck on their fingers. Sticking is a condition that must be removed as soon as possible because it may cause a serious problem that can lead up to the necrosis in the finger. Many methods have been described in the literature for removing the stuck rings. In this report, we presented a case where a ring made of a thick and hard metal alloy that causes sticking and infection in the finger, was removed with a diamond tip high-speed motor used in spinal surgery unlike conventional methods, and the patient was treated without any sequel.

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Section: Case Reportmentioning

confidence: 99%

Removing the ring stuck on finger with a high speed motor: a case report

Ceylan¹

2019

Ann Clin Anal Med

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“…On the other hand, these rings have very low flexibility and model studies show that they may be shattered with locking pliers [ 2 , 3 ]. This approach has now been applied clinically to a patient shortly before delivery.…”

Section: Introductionmentioning

confidence: 99%

Removal of a Tungsten Carbide Ring from the Finger of a Pregnant Patient: A Case Report Involving 2 Emergency Departments and the Internet

Moser

Exadaktylos

Radke

2016

Case Reports in Emergency Medicine

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Introduction. Destructive or nondestructive procedures may be used to remove rings from injured fingers. Because of their hardness, tungsten carbide rings present special problems. Case Presentation. The patient was a 33-year-old woman, two weeks before delivery, with a swollen and reddened ring finger. It was decided to remove a tungsten carbide ring from her ring finger. This was achieved by shattering the ring with locking pliers. The patient's ring finger recovered fully.

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“…[2; 3; 4; 5] The pocket is located in the gp41 N-heptad repeat (NHR) trimeric coiled coil (residues 565–581, uniprot entry P04578) and is occupied by C-heptad repeat (CHR) helices (residues 628–635) during the gp41 conformational transition that accompanies fusion. [6] There are over 50 structures that include this pocket in the Protein Data Bank (PDB), and they display a wide variety of side chain conformations depending on the composition of the complexes[7] and even crystal space group. [3; 5] The result is significant variation in shape and electrostatics of the pocket, limiting the accuracy of computational predictions.…”

Section: Introductionmentioning

confidence: 99%

NMR-assisted computational studies of peptidomimetic inhibitors bound in the hydrophobic pocket of HIV-1 glycoprotein 41

Gochin

Whitby

Phillips

et al. 2013

J Comput Aided Mol Des

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Due to the inherently flexible nature of a protein – protein interaction surface, it is difficult both to inhibit the association with a small molecule, and to predict how it might bind to the surface. In this study, we have examined small molecules that mediate the interaction between a WWI motif on the C-helix of HIV-1 glycoprotein-41 and a deep hydrophobic pocket contained in the interior N-helical trimer. Association between these two components of gp41 leads to virus–cell and cell–cell fusion, which could be abrogated in the presence of an inhibitor that binds tightly in the pocket. We have studied a comprehensive combinatorial library of α-helical peptidomimetics, and found that compounds with strongly hydrophobic side chains had the highest affinity. Computational docking studies produced multiple possible binding modes due to the flexibility of both the binding site and the peptidomimetic compounds. We applied a transferred paramagnetic relaxation enhancement (PRE) experiment to two selected members of the library, and showed that addition of a few experimental constraints enabled definitive identification of unique binding poses. Computational docking results were extremely sensitive to side chain conformations, and slight variations could preclude observation of the experimentally validated poses. Different receptor structures were required for docking simulations to sample the correct pose for the two compounds. The study demonstrated the sensitivity of predicted poses to receptor structure and indicated the importance of experimental verification when docking to a malleable protein – protein interaction surface.

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A Method for the Removal of Tungsten Carbide Rings

Cited by 15 publications

References 7 publications

Removing the ring stuck on finger with a high speed motor: a case report

Removing the ring stuck on finger with a high speed motor: a case report

Removal of a Tungsten Carbide Ring from the Finger of a Pregnant Patient: A Case Report Involving 2 Emergency Departments and the Internet

NMR-assisted computational studies of peptidomimetic inhibitors bound in the hydrophobic pocket of HIV-1 glycoprotein 41

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