A method for optical imaging and monitoring of the excretion of fluorescent nanocomposites from the body using artificial neural networks

Sarmanova, Olga; Burikov, Sergey; Доленко, С. А.; Isaev, Igor; Laptinskiy, Kirill; Prabhakar, Neeraj; Karaman, Didem Şen; Rosenholm, Jessica M.; Shenderova, Olga; Dolenko, Tatiana A.

doi:10.1016/j.nano.2018.03.009

Cited by 22 publications

(6 citation statements)

References 61 publications

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“…The development of bioimaging allows in vivo determination of the impact of pharmaceuticals on cells. Dyes [1][2][3], quantum dots [1,2], carbon nanoparticles [3][4][5][6][7] and up-conversion luminescence fluoride nanoparticles [1,8,9] are used as biosensors. Fluorides possess chemical stability and high values for up-conversion luminescence quantum yields [10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Study of stability of luminescence intensity of b-NaGdF4:Yb:Er nanoparticle colloids in aqueous solution

Kormshchikov¹,

Voronov²,

Burikov³

et al. 2021

Nanosystems: Phys. Chem. Math.

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Hexagonal modification β-NaGdF 4 :Yb:Er with a particle size of 24 nm was synthesized by the solvothermal technique. Concentrated aqueous colloids of nanoparticles were prepared using polyvinylpyrrolidone as the surfactant. The study of the luminescence characteristics for 25 days revealed that the luminescence intensity did not significantly change and hydrolysis of nanoparticles was not observed.

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Section: Introductionmentioning

confidence: 99%

Study of stability of luminescence intensity of b-NaGdF4:Yb:Er nanoparticle colloids in aqueous solution

Kormshchikov¹,

Voronov²,

Burikov³

et al. 2021

Nanosystems: Phys. Chem. Math.

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“…Nanodiamonds are good adsorbents of various substances. − The corresponding functionalization of the ND surface provides it with high selective adsorption activity for heavy metal ions, nitrates, , proteins and DNA molecules, − drugs, , viruses, etc. It was shown by many authors that metal ions, nitrates, proteins, e.g., cytochrome c, or many drugs such as doxorubicin are adsorbed on the surface of nanodiamonds through physical adsorption.…”

Section: Introductionmentioning

confidence: 99%

Bilayer Adsorption of Lysozyme on Nanodiamonds in Aqueous Suspensions

Vervald

Burikov

et al. 2020

J. Phys. Chem. C

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The interactions of one of the most famous enzymes, lysozyme, with carboxylated nanodiamonds in water were studied. It was found that stable complexes are formed as a result of lysozyme adsorption on the surface of nanodiamonds. Based on the obtained adsorption isotherms and change in the fluorescence of nanodiamonds during the adsorption of lysozyme on them, it is concluded that lysozyme is adsorbed on carboxylated nanodiamonds in two layers. Numerical estimates and IR absorption spectroscopy data showed that the lysozyme has different adsorption orientations in the first and second layers, with preferential side-on and end-on orientations, correspondingly. Moreover, in the first layer, lysozyme undergoes significant conformational changes. The enzymatic activity of adsorbed lysozyme in both layers is discussed.

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“…Studying different intracellular biological processes dictates the need to develop new nano-scale sensors/markers. Nowadays, a promising nanomaterial are carbon dots (CD) possessing a unique combination of properties that provide for active application of these nanoparticles for different biomedical purposes [1][2][3][4]. Thus, CD have an intensive photoluminescence (PL) in the visible spectrum range: the luminescence quantum yield is about tens of percents [5,6].…”

Section: Introductionmentioning

confidence: 99%

Dependence of photoluminescence of carbon dots with different surface functionalization on hydrogen factor of water

Yu.

Laptinskiy

Kasyanova

et al. 2022

Optics and Spectroscopy

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The pH dependences of the photoluminescence of carbon dots synthesized by the hydrothermal method with polyfunctional and monofunctional (carboxylated and hydroxylated) surfaces have been studied. As a result of the analysis of the obtained photoluminescence and absorption spectra of aqueous suspensions of all studied types of carbon dots at different pH values, a significant effect of the acidity of the environment of nanoparticles on their optical properties was found. It has been found that the greatest changes in the spectral characteristics of absorption and photoluminescence of carbon dots with COOH, OH, and NH2 surface groups appear in the pH ranges of 2-5 and 8-12. The obtained results are explained are explained by the processes of protonation/deprotonation of the surface groups of carbon dots. Keywords: carbon dots, surface functionalization, absorption spectroscopy, photoluminescence, hydrogen index, deprotonation.

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A method for optical imaging and monitoring of the excretion of fluorescent nanocomposites from the body using artificial neural networks

Cited by 22 publications

References 61 publications

Study of stability of luminescence intensity of b-NaGdF4:Yb:Er nanoparticle colloids in aqueous solution

Study of stability of luminescence intensity of b-NaGdF4:Yb:Er nanoparticle colloids in aqueous solution

Bilayer Adsorption of Lysozyme on Nanodiamonds in Aqueous Suspensions

Dependence of photoluminescence of carbon dots with different surface functionalization on hydrogen factor of water

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