Surfactant assisted co-precipitation method for preparing ZnMnO3 perovskites. The as-synthesized nanoflakes are well characterized by using numerous microscopic and spectroscopic methods which confirmed that ZnMnO3 has high crystalline nature and desired functional groups with nanoflake-like morphology. The synthesized ZnMnO3 were fabricated as the electrode material to determine biologically important as well as priority organic pollutant N-hydroxysuccinimide (NHS). The improved sensing performance of ZnMnO3 towards NHS with outstanding sensitivity, and selectivity in the presence of a 50-fold excess concentration of metal ions and amino acids. The NHS sensor at ZnMnO3/GCE exhibits wide dynamics ranging from 0.01 to 530.6 µM with a superior detection limit of 0.04 µM. Furthermore, the proposed sensor has utilized by practical applicability of NHS detection in the spiked urine samples that achieved better recoveries.