A metal-free near-infrared fluorescent probe for tracking the glucose-induced fluctuations of carbon monoxide in living cells and zebrafish

Wang, Zuokai; Liu, Caiyun; Wang, Xin; Duan, Qingxia; Jia, Pan; Zhu, Hanchuang; Li, Zilu; Zhang, Xue; Ren, Xiaohua; Zhu, Baocun; Sheng, Wenlong

doi:10.1016/j.snb.2019.04.084

Cited by 50 publications

(22 citation statements)

References 60 publications

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“…Mapping of endogenous CO in living cells and zebra fish for up‐regulation of heme‐oxygenase (OH‐1) caused by glucose deprivation and down‐regulation of OH‐1 inhibited by high glucose were effectively recorded. Thus, along with CO detection fluctuation of CO in living cells and animals in pathophysiological process was demonstrated for the first time in literature . But, very recently Wang et al.…”

Section: Fluorescent Probes For Non‐targetable Co Detection In Livingmentioning

confidence: 95%

“…Thus, along with CO detection fluctuation of CO in living cells and animals in pathophysiological process was demonstrated for the first time in literature. [62] But, very recently Wang et al makes one striking report about the authenticity of the chemical transformation occurring, i. e. transformation of the nitro group to amine due to CO gas. [63] They reported that after a prolonged purging of CO gas no observable spectroscopic changes were occurring and NIR-CO is not a general CO probe.…”

Section: Fluorescent Probes For Non-targetable Co Detection In Livingmentioning

confidence: 99%

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Recent Advances in Fluorescence Light‐Up Endogenous and Exogenous Carbon Monoxide Detection in Biology

Mukhopadhyay

Sarkar

Chattopadhyay

et al. 2020

Chemistry An Asian Journal

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Considerable attention has been paid by the scientific community to detect toxic carbon monoxide (CO) in sub-cellular organelles like mitochondria, lysosomes, nuclei, etc. due to their generation and accumulation through numerous biological processes and their role as signal transducer, therapeutics, etc. Various methods are also available for detection of CO, but fluorescence light-up detection is considered the best due to its easy and accurate sensing capability. As of now, no review is available in the literature dedicated to fluorescent detection of only CO both in vitro and in vivo, but considering the huge amount of work reporting every year, it is necessary to have an account of all the recent significant works devoted to it. This review will give special attention to the most noteworthy development of fluorescent light-up probes for the detection of cellular and sub-cellular targetable CO starting from 2012 and emphasizing also the mechanism of action and the applications.

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Section: Fluorescent Probes For Non‐targetable Co Detection In Livingmentioning

confidence: 95%

Section: Fluorescent Probes For Non-targetable Co Detection In Livingmentioning

confidence: 99%

Recent Advances in Fluorescence Light‐Up Endogenous and Exogenous Carbon Monoxide Detection in Biology

Mukhopadhyay

Sarkar

Chattopadhyay

et al. 2020

Chemistry An Asian Journal

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show abstract

“…Then two examples of uorescent probes, NIR-CO and CORM3-green, based on the nitro group reduction reaction were reported by Zhu and Feng, respectively (probes 52 and 53). 70,71 Probe 52 was synthesized with TCF derivatives and designed through regulating the ICT process of the probe. When the nitro group of the probe 52 was directly reduced by CO to an amino group, the inhibited ICT process was released, which caused the probe to generate an off-on NIR uorescence signal (665 nm).…”

Section: Nitro Reductionmentioning

confidence: 99%

Small-molecule fluorescent probes for imaging gaseous signaling molecules: current progress and future implications

et al. 2020

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“…姜国玉等 [68] [70] , 实现了 MCF-7 细胞溶酶体中 CO 检测. 朱宝存等 [71] [4,27] . 目前, 有机 photoCORMs 根据光反应的官能团大致分为三类, 即不饱和环二酮类、羧酸类以及羟基黄酮类.…”

Section: Co 有机荧光探针设计与合成unclassified

Progress in Organic Fluorescent Probes and Photocontrolled Releasers for Carbon Monoxide

Li¹,

Xu²,

Zhang³

et al. 2021

Acta Chimica Sinica

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Carbon monoxide (CO), an extremely important gasotransmitter, plays a critical role in a variety of physiological and pathological events, thus having been considered as a pharmaceutical activity compound with broad medical application. The physiological effects of CO are determined by its dose and spatial location. Therefore, the specific recognition of CO and its controllable supplying are of great significance for understanding and effectively utilizing its physiological and pathological effects. Fluorescence detection and photocontrolled releasing have been widely applied to track and carry active molecules in cells, tissues and in vivo in view of their unique spatiotemporal controllability and noninvasive capacity. Herein, the research progress of CO organic fluorescent probes and photocontrolled releasers in recent years is reviewed, focusing on their recognition mechanism, release mechanism and biological applications. Finally, the application prospects and challenges are discussed.

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A metal-free near-infrared fluorescent probe for tracking the glucose-induced fluctuations of carbon monoxide in living cells and zebrafish

Cited by 50 publications

References 60 publications

Recent Advances in Fluorescence Light‐Up Endogenous and Exogenous Carbon Monoxide Detection in Biology

Recent Advances in Fluorescence Light‐Up Endogenous and Exogenous Carbon Monoxide Detection in Biology

Small-molecule fluorescent probes for imaging gaseous signaling molecules: current progress and future implications

Progress in Organic Fluorescent Probes and Photocontrolled Releasers for Carbon Monoxide

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