A metal-free catalytic system for the oxidation of benzylic methylenes and primary amines under solvent-free conditions

Base metal-catalyzed benzylic oxidation of (aryl)(heteroaryl)methanes with molecular oxygen

“…Due to the activation, the formation of the corresponding ketones and aldehydes becomes feasible under mild conditions. Oxidations of this kind using Oxone ® [10–11], NaOCl [12] or especially peroxides [13–19] as the terminal oxidant are quite numerous. However, transformations using molecular oxygen are rare.…”

Common metal of copper(0) as an efficient catalyst for preparation of nitriles and imines by controlling additives

“…5 On this basis, Savelli reported that primary amines can be converted into nitriles using nickel peroxide as a catalyst, generated in situ from nickel and potassium persulfate as a co-oxidant, in a biphasic water-dichloromethane reaction. 6 It has been reported that TBA 4 [a-H 4 SiW 11 O 39 ] can act as a heterogeneous catalyst for the dehydration of primary amides to form the corresponding nitriles. 7 Yanada described a new C-C triple bond cleavage reaction with NIS and TMSN 3 to achieve the corresponding nitriles.…”

Ultrathin mesoporous NiCo2O4 nanosheets as an efficient and reusable catalyst for benzylic oxidation

“…The 20 initial weight loss of 5.6 % accompanied by an endothermic reaction below 150 o C is assigned to the loss of adsorbed water and the evaporation of intercalated water molecules. The subsequent weight loss of 21.6 % at 150-300 o C and a broad exothermic peak at 280 o C is due to the loss of water produced by 25 the decomposition and dehydroxylation of Co(OH) 2 hexane, isopropylalcohol, acetone, toluene and acetonitrile are 10 employed as the solvent, respectively (entry 2-6). This suggests that the aprotic solvents with larger dielectric constant are beneficial to the enhancing of the conversion of 4,4'difluorobenzophenone.…”

“…[1][2][3] The development of 20 catalysts for benzylic oxidation has therefore attracted considerable interest. In the past decades, tremendous efforts had been devoted to transition-metal catalysts involving Cr, 4,5 Mn, 6,7 Bi, 1 Cu, 8 V, 9,10 Rh, 11 Au 12 , and Fe 13 for benzylic oxidation reactions.…”