A metabolomic approach to lung cancer

Metabolomics provide new insights on lung cancer staging and discrimination from chronic obstructive pulmonary disease

“…Therefore, metabolomic-based studies have been extensively used for disease recognition, prognosis, predicting response to treatment and recovery monitoring. Recently, numerous COPD and lung cancer studies have revealed the great potential of metabolomic-based approaches in disease diagnostics and stratification [19][20][21][22][23][24][25]. Moreover this molecular technique, based on laboratory analysis of small blood sample, is minimally invasive for patient.…”

Metabolomics in cell culture—A strategy to study crucial metabolic pathways in cancer development and the response to treatment

“…Metabolic signatures for several cancer types, including colorectal [29][30][31], breast [32][33][34], pancreatic [35][36][37], liver [38,39], ovarian [40][41][42], prostate [43,44] and lung [45,46] cancer, have been already reported. The potential clinical applications of metabolomics in oncology have already been reviewed [47].…”

Assessment of the Efficacy of Anticancer Drugs by Amino Acid Metabolomics Using Fluorescence Derivatization-HPLC

“…Importantly, these amino acids may be of interest as candidate markers, since the results obtained following the 5-FU and CDDP-treatments support the findings of previous studies. [31][32][33] However, further research is warranted to confirm the selection of amino acids and to evaluate their relationships with different anticancer mechanisms of action.…”