A meta-analysis on the efficacy of the ropivacaine infiltration in comparison with other dental anesthetics

Figueroa-Fernández, Norma Patricia; Hernández-Miramontes, Ycenna Ailed; Alonso-Castro, Ángel Josabad; Isiordia-Espinoza, Mario Alberto

doi:10.1007/s00784-021-03965-x

Cited by 4 publications

(4 citation statements)

References 47 publications

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“…In this study, ropivacaine was used as a local anesthetic, mainly on the basis of ropivacaine's advantages of sensory and motor nerve separation and less influence on postoperative movement, and compared with other local anesthetics, ropivacaine also has advantages of low cardiac and central toxicity and long acting time [20]. A series of studies have shown that its analgesic effect in ophthalmic surgery, dental surgery, and obstetrical and gynecological surgery is superior to that of other anesthetic drugs [21][22][23][24]. Ketorolac is a nonsteroidal anti-inflammatory and analgesic drug that can exert analgesic effects by inhibiting the production of inflammatory pain-causing transmitters.…”

Section: Discussionmentioning

confidence: 99%

The Effects of Periarticular Injection Cocktail in Postoperative Analgesia after Bilateral Unicompartmental Knee Arthroplasty

Wang¹,

Zhao

Guo

et al. 2022

Computational and Mathematical Methods in Medicine

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Objective. This study was conducted to compare postoperative pain and functional recovery in bilateral unicompartmental knee arthroplasty (UKA) and unilateral UKA after cocktail therapy. Methods. A total of 240 patients who received unilateral UKA and bilateral UKA in our orthopedic department from February 2019 to April 2020 were collected. The general clinical data was recorded and compared between the two groups of subjects, and the time of postoperative landing was recorded separately for both groups. A visual analogue scale (VAS) was used to record the patients’ pain at 1, 7, and 14 days postoperatively, as well as the range of motion of the affected limb at 1, 7, 14 days, and 3 months postoperatively and the hospital for special surgery (HSS) knee score of the knee at 1 month postoperatively. Results. After cocktail injection analgesia, unilateral patients with knee surgery got off the ground and walked significantly earlier than patients with bilateral surgery, while there was no significant difference between the two groups in terms of pain at 1, 7, and 14 days after surgery, range of motion of the affected limb at 1, 7, 14 days, and 3 months after surgery, and knee HSS score at 1 month after surgery. Conclusion. Periarticular cocktail injection significantly reduces postoperative pain in patients, and bilateral UKA surgery can be used as satisfactory as unilateral UKA in clinical practice.

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Section: Discussionmentioning

confidence: 99%

The Effects of Periarticular Injection Cocktail in Postoperative Analgesia after Bilateral Unicompartmental Knee Arthroplasty

Wang¹,

Zhao

Guo

et al. 2022

Computational and Mathematical Methods in Medicine

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“…The main advantages of this study include an adequate methodology, rigorous and conservative statistical methods, and the available evidence with a lower risk of bias to perform a powerful pooled analysis [ 29 , 30 , 32 , 33 , 34 , 35 , 49 ]. Local administration of dexamethasone was performed via the submucosal, supraperiosteal, or intraligamentary routes, and different doses of dexamethasone were used.…”

Section: Discussionmentioning

confidence: 99%

“…The influence of the weight of each study on the results of the meta-analysis was evaluated through a sensitivity study. A p -value of ≤0.05 and odds ratio or a mean difference ≥ 1 (a positive or negative value on a two-sided test) within a 95% confidence interval was considered to be a statistically significant difference [ 29 , 30 , 32 , 33 , 34 , 35 ].…”

Section: Methodsmentioning

confidence: 99%

Dexamethasone Increases the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis

et al. 2022

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Inferior alveolar nerve block (IANB) has a high failure rate in subjects with symptomatic irreversible pulpitis (SIP). It has been suggested that drugs with anti-inflammatory activity could improve the efficacy of the anesthetic used for IANB. The aim of this study was to assess the effect of dexamethasone on the success of dental anesthesia in patients with SIP. An information search was performed using PubMed and Google Scholar. The risk of bias of the included studies was evaluated with the Cochrane Collaboration’s risk-of-bias tool. The anesthetic success rate, pain intensity (VAS), and adverse effects were extracted. Data were analyzed using the Mantel–Haenszel test and odds ratio or the inverse variance and standardized mean difference. Dexamethasone increased the anesthetic success in comparison with placebo (n = 502; p < 0.001; OR = 2.59; 95% CIs: 1.46 to 4.59). Moreover, patients who were given dexamethasone had lower pain scores at 6 h (n = 302; p < 0.001; MD= −1.43; 95% CIs: −2.28 to −0.58), 12 h (n = 302; p < 0.0001; MD = −1.65; 95% CIs: −2.39 to −0.92), and 24 h (n = 302; p < 0.0008; MD = −1.27; 95% CIs: −2.01 to −0.53) when compared with placebo. In conclusion, the systemic administration of dexamethasone increases the anesthetic success rate and improves pain management in patients with SIP.

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“…Furthermore, the funnel plots were employed to assess the publication bias of the included clinical studies. A p -value ≤ of 5% (0.05), with an OR ≥ 1 within a 95% confidence interval (CIs), was considered a statistical difference [ 32 , 35 , 36 , 37 , 38 ].…”

Section: Information Searchmentioning

confidence: 99%

Local Tramadol Improves the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis

et al. 2022

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Symptomatic irreversible pulpitis is a painful clinical condition with a broad inflammatory component. Dental anesthesia in these patients is affected by the inflammatory process, reporting a high incidence of anesthesia failure. The aim of this systematic review and meta-analytical evaluation was to determine the effect of pre-treatment with tramadol in patients with symptomatic irreversible pulpitis, as well as for pain control and adverse effects. This study was registered in PROSPERO (ID: CRD42021279262). PubMed was consulted to identify clinical investigations comparing tramadol and placebo/local anesthetics in patients with symptomatic irreversible pulpitis. Data about the anesthesia, pain control, and adverse effects were extracted. Both the anesthetic success index and the adverse effects of local tramadol and placebo were compared with the Mantel–Haenszel test and odds ratio. Data analysis showed that the local administration of tramadol increased the anesthetic success rate when compared to placebo in patients with symptomatic irreversible pulpitis (n = 228; I2 = 0; OR = 2.2; 95% CIs: 1.30 to 3.79; p < 0.004). However, local administration of tramadol increased the risk of adverse effects when compared to placebo/local anesthetics (n = 288; I2 = 0; OR = 7.72; 95% CIs: 1.37 to 43.46; p < 0.02). In conclusion, this study shows that the local administration of tramadol increases the anesthetic success index when compared to placebo in patients with symptomatic irreversible pulpitis.

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A meta-analysis on the efficacy of the ropivacaine infiltration in comparison with other dental anesthetics

Cited by 4 publications

References 47 publications

The Effects of Periarticular Injection Cocktail in Postoperative Analgesia after Bilateral Unicompartmental Knee Arthroplasty

The Effects of Periarticular Injection Cocktail in Postoperative Analgesia after Bilateral Unicompartmental Knee Arthroplasty

Dexamethasone Increases the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis

Local Tramadol Improves the Anesthetic Success in Patients with Symptomatic Irreversible Pulpitis: A Meta-Analysis

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