A meta‐analysis of the placebo response in vitiligo: Causes and consequences for the interpretation of clinical trials
Reinhart Speeckaert,
Marijn M. Speeckaert,
Nanja van Geel
Abstract:The current understanding of the placebo response in vitiligo is limited. Nonetheless, it is difficult to compare the outcomes of vitiligo trials if the repigmentation rates in placebo patients vary significantly. We conducted a meta‐analysis of the placebo response in vitiligo trials. Overall, repigmentation rates in patients receiving placebo were 22%, ranging substantially from 0 to 60%. Repigmentation (>25%) was still relatively common for placebo (9.35%), but fell to 5% when >50% improvement was ana… Show more
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