A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis

Srikanth, Velandai; Fryer, J. G.; Zhai, Guangju; Winzenberg, Tania; Hosmer, David W.; Jones, Graeme

doi:10.1016/j.joca.2005.04.014

Cited by 977 publications

(744 citation statements)

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“…Osteoarthritis of the knee is more common in women than men [7,33]. Women lose articular cartilage at four times the annual rate of men in the proximal tibia and three times in the patella [9].…”

Section: Introductionmentioning

confidence: 99%

Implant Survival, Knee Function, and Pain Relief After TKA: Are There Differences Between Men and Women?

O’Connor

2011

Clinical Orthopaedics &Amp; Related Research

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Background As efforts continue to improve the results of TKA, the potential influence of sex and gender on longterm survival of implants, knee function, pain relief, and patient satisfaction remains relevant, particularly given the increased incidence of osteoarthritis of the knee in women and reports that women derive equal benefit from TKA. Questions/purposes This article reviews the literature pertinent to the question of whether long-term survival, knee function, pain relief, and patient satisfaction after TKA differ between men and women. Methods Large clinical series ([ 1000 patients) published in the last 10 years were identified in PubMed and reviewed. Results Men may be at higher risk of revision surgery than women. Sex/gender has been consistently shown to impact both function and pain relief both before and after TKA. Although women achieve at least the same degree of functional improvement as men, women have worse preoperative physical function and do not reach the same final level of physical function as men. Likewise women may have similar or even greater improvement in pain after arthroplasty than men but still have final pain scores that are less favorable. Conclusions Further research is required to understand the sex and gender differences contributing to implant survival, physical function, and pain relief after TKA.Strategies need to be developed to identify any patient who is at higher risk of implant failure, suboptimal postoperative function, and incomplete pain relief.

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Section: Introductionmentioning

confidence: 99%

Implant Survival, Knee Function, and Pain Relief After TKA: Are There Differences Between Men and Women?

O’Connor

2011

Clinical Orthopaedics &Amp; Related Research

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“…Neck pain may become chronic in 22% of women and 16% of men and approximately 30% will lead to functional disability. Four clinical manifestations are often encountered, including: pure cervical syndrome, conjugated more commonly, basalar vertebro syndrome and rarely osteoarthritic myelopathy [3,4].…”

Section: Introductionmentioning

confidence: 99%

Prognostic Impact of Hypermethylated SFRP1, SFRP2 and Over Expression of CD25 in Acutemyeloid Leukemia

Nigm¹,

Elfadle²,

Elrahman³

2016

Clon Transgen

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Background: More than 50% of people aged 40 years suffer from cervicarthrosis, This disease constitutes a public health problem. For this the decade 2001-2010 was declared by the WHO as "decade of the bones and joints". Objective:To determine the epidemiological and clinical profile of the Congolese patients suffering about cervical arthrosis and to study the evolution of modification of cervical lordosis with a view to improving physical treatment.Methods: This case study was conducted at the University clinics of Kinshasa during the year 2011 to 2016. 35 patients' male and female, suffering about cervical arthrosis, were included. The different angulations of the cervical lordosis measured with an appropriate software. The height of the cervical spine measured by a caliper was 14 cm on average. The load exerted by the head on the cervical spine is directly function of lordosis and the height of the vertebra was calculated. Results:Of the 35 patients, 34.3% men and 65.7 women. Age ranged from 30 to 80 years and the highest incidence of cervicarthrosis was between 61 and 65 years (20%). The clinic was dominated by cervical pain (80%) and irradiated pain in 37%. Other signs (blurred vision, headache, dizziness) were poorly represented. For radiographic signs: cervical lordosis was eliminated either decreased in 91% of cases, followed by inter-somatic pinching (68%), ductal stenosis (62%) and osteophytosis in only 20% of cases. However, osteoarthritic myelopathy is extremely rare (2%). Variation of the head load (in Kg) on each vertebra of the cervical spine from C1 to C7 and from 0 to 45° depending on the level of the vertebra and the degree of cervical lordosis. The force increases from C1 to C7 and from 45° to 0° following an arithmetic progression. Conclusion:This study has just highlighted the importance of the cervical lordosis spine in the diagnosis of cervical arthrosis and showed the important role of cervical lordosis in the variation of head load on each vertebra.Citation: Meya KG, Nsitwayizatadi MB, Nkakudulu BKH, Miangindula B, Mabanza M, et al. (2017) Epidermological and Clinical Profile of CervicarthrosisPatients. Clon Transgen 6: 158.

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“…Osteoarthritis (OA), the most common form of arthritis, is a disabling chronic disease with significant clinical and economic implications (1)(2)(3)(4)(5). Key OA risk factors include age, sex, obesity, and trauma (6)(7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

“…Key OA risk factors include age, sex, obesity, and trauma (6)(7)(8)(9). As the Canadian population is aging and obesity is increasing, OA incidence and prevalence are expected to continue rising (4,5,(7)(8)(9)(10). The Arthritis Alliance of Canada reported that 25% of Canadians and almost 30% of the labor force are expected to have OA by 2040 (11).…”

Section: Introductionmentioning

confidence: 99%

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Estimating the Burden of Osteoarthritis to Plan for the Future

Marshall

Vanderby

Barnabé

et al. 2015

Arthritis Care & Research

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Objective. With aging and obesity trends, the incidence and prevalence of osteoarthritis (OA) is expected to rise in Canada, increasing the demand for health resources. Resource planning to meet this increasing need requires estimates of the anticipated number of OA patients. Using administrative data from Alberta, we estimated OA incidence and prevalence rates and examined their sensitivity to alternative case definitions. Methods. We identified cases in a linked data set spanning 1993 to 2010 (population registry, Discharge Abstract Database, physician claims, Ambulatory Care Classification System, and prescription drug data) using diagnostic codes and drug identification numbers. In the base case, incident cases were captured for patients with an OA diagnostic code for at least 2 physician visits within 2 years or any hospital admission. Seven alternative case definitions were applied and compared. Results. Age-and sex-standardized incidence and prevalence rates were estimated to be 8.6 and 80.3 cases per 1,000 population, respectively, in the base case. Physician claims data alone captured 88% of OA cases. Prevalence rate estimates required 15 years of longitudinal data to plateau. Compared to the base case, estimates are sensitive to alternative case definitions. Conclusion. Administrative databases are a key source for estimating the burden and epidemiologic trends of chronic diseases such as OA in Canada. Despite their limitations, these data provide valuable information for estimating disease burden and planning health services. Estimates of OA are mostly defined through physician claims data and require a long period of longitudinal data.

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A meta-analysis of sex differences prevalence, incidence and severity of osteoarthritis

Cited by 977 publications

References 53 publications

Implant Survival, Knee Function, and Pain Relief After TKA: Are There Differences Between Men and Women?

Implant Survival, Knee Function, and Pain Relief After TKA: Are There Differences Between Men and Women?

Prognostic Impact of Hypermethylated SFRP1, SFRP2 and Over Expression of CD25 in Acutemyeloid Leukemia

Estimating the Burden of Osteoarthritis to Plan for the Future

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