A meta-analysis of implant-based breast reconstruction and timing of adjuvant radiation therapy

Racial disparities in postmastectomy breast reconstruction: National trends in utilization from 2005 to 2014

“…The American Society of Plastic Surgeons recommends that patients who choose TE/I reconstruction in the setting of radiotherapy should be carefully counseled on the risk of complications, such as reconstructive failure . Consequently, some surgeons recommend that patients consider autologous reconstruction when radiotherapy is involved in their breast cancer management . For autologous reconstruction, evidence of an association between these factors and TRAM flap versus DIEP flap reconstruction is inconsistent .…”

“…Several studies have assessed the relation between radiotherapy and TE/I versus autologous reconstruction. 34 The American Society of Plastic Surgeons recommends that patients who choose TE/I reconstruction in the setting of radiotherapy should be carefully counseled on the risk of complications, such as reconstructive failure. 35 Consequently, some surgeons recommend that patients consider autologous reconstruction when radiotherapy is involved in their breast cancer management.…”

“…35 Consequently, some surgeons recommend that patients consider autologous reconstruction when radiotherapy is involved in their breast cancer management. 34 For autologous reconstruction, evidence of an association between these factors and TRAM flap versus DIEP flap reconstruction is inconsistent. 23 One study assessing the relation between radiation therapy and type of free-flap reconstruction reported no significant differences in complications.…”

International multidisciplinary expert panel consensus on breast reconstruction and radiotherapy

“…The generic reference to ‘breast reconstruction’ was intended to capture all articles addressing the type and timing of breast reconstruction. Two authors independently reviewed abstracts of all studies published between 1985 and 2014, and the full texts of those studies published in 2015–2017. Levels of clinical evidence (LoE) were evaluated for each publication and scored from I to V by employing Oxford criteria.…”

Breast cancer fractionation patterns: Why aren't they uniform, and should they be?

“…However, neither of these trials included patients undergoing immediate reconstruction. Radiation therapy has a substantial impact on the cosmetic results, complication rates, and patient satisfaction with breast reconstruction surgery . Different fractionation schemes might have subtly different effects in exacerbating the inflammatory reaction thought to result in capsular fibrosis and other complications for patients having prosthetic reconstruction.…”