Abstract:Background and Aims: Although observational studies have reported correlations between inflammatory bowel disease (IBD) and aging, there is no evidence supporting causal relationships between the two.
Methods: Summary data from the Genome-Wide Association Study (GWAS) were subjected to two-sample and bidirectional Mendelian randomization (MR) to assess the causal relationships between biomarkers of IBD and aging. Following IEU GWAS database screening and single nucleotide polymorphism filtering, various MR me… Show more
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