Background: The purpose of this study was to quantify the stabilizing effect of anterior cervical fusion and plating (ACFP) on various grades of simulated flexion/distraction injuries to the human cervical spine. Material and Methods: A finite element approach was used. Digitized data from computed tomography of a human cervical spine were taken to generate a threedimensional, anisotrophic, linear finite element model (FEM) C4-C7. Based on this FEM of the intact segments (FEM 1), an additional model was generated: FEM with simulation of ACFP of C5/6 using bicortical screws (FEM 2). Loading of each FEM was simulated using pure moments of ± 2.5 Nm in flexion/extension, left/right axial rotation, and left/right lateral bending. For validation of the models, their predictions of range of motion (ROM) C5/6 were compared to the results of a previous, corresponding in vitro study, using human segments C4-C7 surgically altered with the same implants. Results: Results obtained by the FEM 1 and 2 for each loading case were within one standard deviation of the results of the corresponding in vitro study. Thus, alterations of FEM 2 were used in the following to predict the changes in flexibility C5/6 after stepwise transection of the posterior ligaments. An increase in ROM occurred in each loading case after transection of single components, which was pronounced in rotation and bending following removal of the capsules. Conclusions: ACFP may be sufficient for flexion-distraction injuries if the capsular ligaments and facets are not injured.