A Markov analysis of azacitidine and venetoclax vs induction chemotherapy for medically fit patients with AML
Mithunan Ravindran,
Lee Mozessohn,
Matthew Cheung
et al.
Abstract:While induction chemotherapy (IC) is the standard of care in medically-fit patients with newly diagnosed acute myeloid leukemia (AML), limited retrospective data indicate that adverse risk patients may benefit from azacitidine and venetoclax (aza-ven). Our goal was to perform a Markov decision analysis to determine whether IC or aza-ven is the optimal induction regimen in this population. Using the TreeAge software, Markov models were created for adverse risk and intermediate risk cohorts. A systematic review … Show more
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