Several authors have explored the role of Venice in diplomacy, given the city-state’s historical significance as a major maritime and trading power. Could the Venice experience teach us about economic diplomacy today? Venice, during its heyday as a maritime republic and a major economic power in the Mediterranean, offers several lessons in economic diplomacy that remain relevant today. While the historical context differs, the principles underlying Venice’s economic success and diplomatic strategies can provide insights into contemporary international relations and economic diplomacy.