A magnetoelastic bioaffinity-based sensor for avidin

Ruan, Chuanmin; Zeng, Ke; Varghese, Oomman K.; Grimes, Craig A.

doi:10.1016/j.bios.2004.01.005

Cited by 41 publications

(23 citation statements)

References 38 publications

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“…The sensor shows a decrease in resonance frequency of approximately 200 Hz over the 1.5-h test period due to the nonspecific adsorption of AP conjugated avidin. The result is consistent with our previous study concerning the nonspecific adsorption of streptavidin on magnetoelastic sensors [31]. It is known that nonspecific adsorption is a problem for biotin-avidin systems used in immunosensor and immunassays [32].…”

Section: Monitoring Of Staphylococcal Enterotoxin Bsupporting

confidence: 94%

Quantification of multiple bioagents with wireless, remote-query magnetoelastic microsensors

et al. 2006

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This paper presents a micromagnetoelastic sensor array for simultaneously monitoring multiple biological agents. Magnetoelastic sensors, made of low-cost amorphous ferromagnetic ribbons, are analogous and complementary to piezoelectric acoustic wave sensors, which track parameters of interest via changes in resonance behavior. Magnetoelastic sensors are excited with magnetic ac fields, and, in turn, they generate magnetic fluxes that can be detected with a sensing coil from a distance. As a result, these sensors are highly attractive, not only due to their small size and low cost, but also because of their passive and wireless nature. Magnetoelastic sensors have been applied for monitoring pressure, temperature, liquid density, and viscosity, fluid flow velocity and direction, and with chemical/biological responsive coatings that change mass or elasticity, various biological and chemical agents. In this paper, we report the fabrication and application of a six-sensor array for simultaneous measurement of Escherichia coli O157:H7, staphylococcal enterotoxin B, and ricin. In addition, the sensor array also monitors temperature and pH so the measurements are independent from these two parameters.

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Section: Monitoring Of Staphylococcal Enterotoxin Bsupporting

confidence: 94%

Quantification of multiple bioagents with wireless, remote-query magnetoelastic microsensors

et al. 2006

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“…More recently, another variation has been demonstrated where hydrogels containing benzo-18-crown-6 coated on microcantilevers were used to create Pb 2+ sensors. [114] In other work utilizing the actuation response of hydrogels, Grimes and co-workers [115,116] demonstrated wireless pH sensors based on integrating pH-responsive hydrogels with magnetoelastic thick films. The sensor device functioned by remotely monitoring the change in resonance frequency resulting from an applied mass load of the magnetoelastic sensor device.…”

Section: Medical and Biological Sensorsmentioning

confidence: 98%

Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology

et al. 2006

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Hydrophilic polymers are the center of research emphasis in nanotechnology because of their perceived “intelligence”. They can be used as thin films, scaffolds, or nanoparticles in a wide range of biomedical and biological applications. Here we highlight recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for these applications. Natural, biohybrid, and synthetic hydrophilic polymers and hydrogels are analyzed and their thermodynamic responses are discussed. In addition, examples of the use of hydrogels for various therapeutic applications are given. We show how such systems' intelligent behavior can be used in sensors, microarrays, and imaging. Finally, we outline challenges for the future in integrating hydrogels into biomedical applications.

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“…Recently, this sensor has been developed for the determination of physical parameters such as pressure, temperature, flow rate and liquid viscosity [11], as well as chemical substances including carbon dioxide, ammonia [11], mercury [12], radon [13] and calcium oxalate [14]. It has also been used to detect biological substances such as glucose [15], trypsin [16], avidin [17], -amylase [18], acid phosphatase [19], M. genitalium [20], and Salmonella typhimurium [21], and monitor biological processes such as the growth of breast cancer cells [22] and M. genitalium [23].…”

Section: Introductionmentioning

confidence: 99%

Determination of uranium in water based on enzyme inhibition using a wireless magnetoelastic sensor

Zhao

Liao

Xiao

et al. 2013

International Journal of Environmental Analytical Chemistry

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A magnetoelastic bioaffinity-based sensor for avidin

Cited by 41 publications

References 38 publications

Quantification of multiple bioagents with wireless, remote-query magnetoelastic microsensors

Quantification of multiple bioagents with wireless, remote-query magnetoelastic microsensors

Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology

Determination of uranium in water based on enzyme inhibition using a wireless magnetoelastic sensor

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