A magnetic nanoparticle based immunoassay for alternariol monomethyl ether using hydrogen peroxide-mediated fluorescence quenching of CdTe quantum dots

Man, Yan; Jin, Xinxin; Fu, Hailong; Pan, Ligang

doi:10.1007/s00604-019-3334-8

Cited by 12 publications

(2 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Man et al reported fluorometric immunoassay by introducing H 2 O 2 -mediated fluorescence quenching of mercaptopropionic acid-capped CdTe QDs (MPA-CdTe QDs) into MNP-based immunoassay for the detection of alternariol monomethyl ether (AME). 157 AME is a mycotoxin produced by the Alternaria species. Herein, free AME from the sample competes with catalase (CAT)-labeled AME to bind to monoclonal antibodies (mAbs) on MNPs.…”

Section: Other Magnetic Bioassay Methodsmentioning

confidence: 99%

Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19

Saha

et al. 2020

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is a threat to the global healthcare system and economic security. As of July 2020, no specific drugs or vaccines are yet available for COVID-19; a fast and accurate diagnosis for SARS-CoV-2 is essential in slowing the spread of COVID-19 and for efficient implementation of control and containment strategies. Magnetic nanosensing is an emerging topic representing the frontiers of current biosensing and magnetic areas. The past decade has seen rapid growth in applying magnetic tools for biological and biomedical applications. Recent advances in magnetic nanomaterials and nanotechnologies have transformed current diagnostic methods to nanoscale and pushed the detection limit to early-stage disease diagnosis. Herein, this review covers the literature of magnetic nanosensors for virus and pathogen detection before COVID-19. We review popular magnetic nanosensing techniques including magnetoresistance, magnetic particle spectroscopy, and nuclear magnetic resonance. Magnetic point-of-care diagnostic kits are also reviewed aiming at developing plug-and-play diagnostics to manage the SARS-CoV-2 outbreak as well as preventing future epidemics. In addition, other platforms that use magnetic nanomaterials as auxiliary tools for enhanced pathogen and virus detection are also covered. The goal of this review is to inform the researchers of diagnostic and surveillance platforms for SARS-CoV-2 and their performances.

show abstract

Section: Other Magnetic Bioassay Methodsmentioning

confidence: 99%

Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19

Saha

et al. 2020

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

show abstract

“…A restricted number of studies covered the determination of the five most relevant ATs (investigated in the present work) and most of them addressed vegetables, fruits and products thereof [3,9,[25][26][27] (excluding cereals and oil seeds). Furthermore, methods based on a simple solid-or liquid-liquid extraction, following the 'dilute and shoot' or QuEChERS protocols, were generally insufficient to achieve sub-µg/kg LOQs in complex matrices [20,28], as required for exposure assessment studies [29,30].…”

Section: Introductionmentioning

confidence: 99%

Determination of Alternaria Toxins in Food by SPE and LC-IDMS: Development and In-House Validation of a Candidate Method for Standardisation

Gonçalves

Tölgyesi²,

Bouten

et al. 2022

Separations

View full text Add to dashboard Cite

Alternaria toxins (ATs) are frequently found contaminants in foodstuffs (e.g., alternariol), often reaching high concentrations (e.g., tenuazonic acid). They can spoil a wide variety of food categories (e.g., cereals, vegetables, seeds and drinks) and storage at fridge temperatures does not prevent the growth of Alternaria fungi. Therefore, reliable and validated analytical methods are needed to protect human health and to ensure a transparent and fair trade. This paper describes new technical features that improved a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the analysis of ATs in tomato, wheat and sunflower seeds. This analytical method should be simple to implement in different laboratories across the EU and thus be an attractive candidate for standardisation. The major element for improvement was the use of isotopically labelled internal standards, only recently commercially available, thereby reducing the sample handling and improving the accuracy of the results. In addition, the sample extraction and the solid-phase extraction (SPE) enrichment/clean-up were fine-tuned, whereas a more suitable analytical column (XSelect HSS T3) with improved selectivity was also employed. Overall, this method shows adequate precision (repeatability < 5.7% RSD; intermediate precision < 7.0% RSD) and trueness (recoveries ranging from 74% to 112%). The limits of quantification in wheat (the most analytically demanding matrix) vary between 0.19 and 1.40 µg/kg. These figures were deemed satisfactory by the European Committee for Standardization (CEN) and have formed the basis for a subsequent interlaboratory validation study. The corresponding standard was published by CEN in 2021.

show abstract

Nitrogen-doped graphene oxide as a catalyst for the oxidation of Rhodamine B by hydrogen peroxide: application to a sensitive fluorometric assay for hydrogen peroxide

et al. 2019

View full text Add to dashboard Cite

A magnetic nanoparticle based immunoassay for alternariol monomethyl ether using hydrogen peroxide-mediated fluorescence quenching of CdTe quantum dots

Cited by 12 publications

References 38 publications

Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19

Magnetic-Nanosensor-Based Virus and Pathogen Detection Strategies before and during COVID-19

Determination of Alternaria Toxins in Food by SPE and LC-IDMS: Development and In-House Validation of a Candidate Method for Standardisation

Nitrogen-doped graphene oxide as a catalyst for the oxidation of Rhodamine B by hydrogen peroxide: application to a sensitive fluorometric assay for hydrogen peroxide

Contact Info

Product

Resources

About