A longitudinal study on the osteoarthritic change of the temporomandibular joint based on 1-year follow-up computed tomography

Lee, Jeong-Yun; Kim, Dae Jung; Lee, Sang-goo; Chung, Jin-Woo

doi:10.1016/j.jcms.2011.10.023

Cited by 29 publications

(28 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…43 However, most of the literature reports only the presence or absence of osteoarthritic changes without providing details regarding location and amount of change. 21,27,[44][45][46][47][48][49] Our results clearly showed that subjects that had experienced long-term history of TMJ OA presented with more marked morphological changes in the mandibular condyle than the ones at initial diagnosis of the disease. Therefore, we may infer that such characteristics are interrelated in a progressive scale, i.e., the longer the subjects presented with signs and symptoms of the disease, the more marked condylar changes may be observed.…”

Section: Discussionmentioning

confidence: 51%

“…17,18 MRIs have provided essential information about disk position, morphology, and integrity. 18,[20][21][22][23][24][25][26] Cone-beam computed tomography (CBCT) has assumed a prominent role in the diagnosis of condylar remodeling. 19 Computed tomography (CT) is generally accepted as the most useful technique for assessing OA changes in the TMJs, being able to provide clinicians and researchers with detailed information on bone remodeling.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Diagnostic index of three-dimensional osteoarthritic changes in temporomandibular joint condylar morphology

Gomes

Jung

et al. 2015

J. Med. Imag.

View full text Add to dashboard Cite

This study aimed to investigate imaging statistical approaches for classifying three-dimensional (3-D) osteoarthritic morphological variations among 169 temporomandibular joint (TMJ) condyles. Cone-beam computed tomography scans were acquired from 69 subjects with long-term TMJ osteoarthritis (OA), 15 subjects at initial diagnosis of OA, and 7 healthy controls. Three-dimensional surface models of the condyles were constructed and SPHARM-PDM established correspondent points on each model. Multivariate analysis of covariance and direction-projection-permutation (DiProPerm) were used for testing statistical significance of the differences between the groups determined by clinical and radiographic diagnoses. Unsupervised classification using hierarchical agglomerative clustering was then conducted. Compared with healthy controls, OA average condyle was significantly smaller in all dimensions except its anterior surface. Significant flattening of the lateral pole was noticed at initial diagnosis. We observed areas of 3.88-mm bone resorption at the superior surface and 3.10-mm bone apposition at the anterior aspect of the long-term OA average model. DiProPerm supported a significant difference between the healthy control and OA group ([Formula: see text]). Clinically meaningful unsupervised classification of TMJ condylar morphology determined a preliminary diagnostic index of 3-D osteoarthritic changes, which may be the first step towards a more targeted diagnosis of this condition.

show abstract

Section: Discussionmentioning

confidence: 51%

Section: Introductionmentioning

confidence: 99%

Diagnostic index of three-dimensional osteoarthritic changes in temporomandibular joint condylar morphology

Gomes

Jung

et al. 2015

J. Med. Imag.

View full text Add to dashboard Cite

show abstract

“…They noted that “many patients are unaware of the deviation in form and the case history is often negative for pain or acute dysfunction”, because “it may well be a remodeling due to changed function”, leading to pain-free adaptive changes of the osseous structures of the TMJ [83]. Therefore, TMJs with signs of osteoarthrosis are not necessarily associated with more symptoms of TMDs than TMJs without osteoarthrosis [84, 85]. On the other hand, clinical signs and symptoms of TMJ osteoarthritis are poorly correlated with osseous changes depicted with computed tomography [86] or CBCT [30].…”

Section: Discussionmentioning

confidence: 99%

Disk displacement, eccentric condylar position, osteoarthrosis – misnomers for variations of normality? Results and interpretations from an MRI study in two age cohorts

et al. 2016

View full text Add to dashboard Cite

BackgroundClinical decision-making and prognostic statements in individuals with manifest or suspected temporomandibular disorders (TMDs) may involve assessment of (a) the position of articular disc relative to the mandibular condyle, (b) the location of the condyle relative to the temporal joint surfaces, and (c) the depth of the glenoid fossa of the temporomandibular joints (TMJs). The aim of this study was twofold: (1) Determination of the prevalence of these variables in two representative population-based birth cohorts. (2) Reinterpretation of the clinical significance of the findings.MethodsFrom existing magnetic resonance imaging (MRI) scans of the TMJs that had been taken in 2005 and 2006 from 72 subjects born between 1930 and 1932 and between 1950 and 1952, respectively, the condylar position at closed jaw was calculated as percentage displacement of the condyle from absolute centricity. By using the criteria introduced by Orsini et al. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:489-97, 1998), a textbook-like disc position at closed jaw was distinguished from an anterior location. TMJ morphology of the temporal joint surfaces was assessed at open jaw by measuring the depth of the glenoid fossa, using the method proposed by Muto et al. (J Oral Maxillofac Surg 52:1269-72, 1994).Frequency distributions were recorded for the condylar and disc positions at closed jaw.Student’s t-test with independent samples was used as test of significance to detect differences of condylar positions between the age cohorts (1930 vs. 1950) and the sexes. The significance levels were set at 5%. First, the results from the measurement of the age cohorts were compared without differentiation of sexes, i.e., age cohort 1930–1932 versus age cohort 1950–1952. Subsequently, the age cohorts were compared by sex, i.e., men in cohort 1930–1932 versus men in cohort 1950–1952, and women in cohort 1930–1932 women men in cohort 1950–1952.ResultsIn both cohorts, condylar position was characterized by great variability. About 50% of the condyles were located centrically, while the other half was either in an anterior or in a posterior position. In both female cohorts, a posterior position predominated, whereas a centric position prevailed among men. Around 75% of the discs were positioned textbook-like, while the remaining forth was located anteriorly. Age had no statistically significant influence on condylar or on disc position. Conversely, comparison between the age groups revealed a statistically significant decrease of the depth of the glenoid fossa in both older cohorts. This age-dependent changes may be interpreted as flattening of the temporal joint surfaces.ConclusionsWe call for a re-interpretation of imaging findings because they may insinuate pathology which usually is not present. Instead, anterior or posterior positions of the mandibular condyle as well as an anterior location of the articular disc should be construed as a variation of normalcy. Likewise, flattening of articular surfaces of the TMJs may be considered ...

show abstract

“…Moreover, previous reports had related DP to degenerative joint disease (DJD) or Osteoarthritis (OA) both Clinically 5 and experimentally 6,7 . DP is seen in about 5-15% of (TMJ) with displaced discs on arthroscopic examination of patients in the late stage [8][9][10] .…”

Section: Introductionmentioning

confidence: 99%

The Efficacy of Simvastatin Drug Injection for Regeneration of Induced Small Perforated TMJ Disc (An Experimental Study)

Ghanem

2017

Egyptian Dental Journal

View full text Add to dashboard Cite

Objectives:The current study aimed to evaluate arthroscopically, macroscopically and histopathologically the efficacy of Simvastatin drug intra-discal injection for stopping degeneration and increasing regeneration of induced perforated TMJ disc.Methodology: Ten goats (20 joints) were incorporated in the study. Stab perforations were performed in all TMJs' discs in both sides of each goat under arthroscopic guidance, on joints of all animals the left TMJ acted as a control group without injecting any solutions after disk perforation, whereas the right TMJ acted as the experimental group by injecting the simvastatin hydrogel in the perforation site.Results: Arthroscopic, macroscopic and histopathological evaluation revealed that the injected perforation sites had higher scores (regeneration) than the non-injected perforation sites. The present study proved that injection of simvastatin hydrogel 5mg/ml promotes autogenously chondrogenic disc repair and retard disc degeneration, which provides an alternative strategy for biological TMJ disc perforations repair in a less expensive and easily applied method.Conclusion: the current study recommended that, arthroscopic simvastatin hydrogel injection can be safely conducted on perforated TMJ disc patients. KEY WORDS:Simvastatin hydrogel injection, perforated TMJ disc, arthroscopic picture and disc regeneration. (1334)

show abstract

A longitudinal study on the osteoarthritic change of the temporomandibular joint based on 1-year follow-up computed tomography

Cited by 29 publications

References 18 publications

Diagnostic index of three-dimensional osteoarthritic changes in temporomandibular joint condylar morphology

Diagnostic index of three-dimensional osteoarthritic changes in temporomandibular joint condylar morphology

Disk displacement, eccentric condylar position, osteoarthrosis – misnomers for variations of normality? Results and interpretations from an MRI study in two age cohorts

The Efficacy of Simvastatin Drug Injection for Regeneration of Induced Small Perforated TMJ Disc (An Experimental Study)

Contact Info

Product

Resources

About