A Longitudinal Study of Bayou Virus, Hosts, and Habitat

McIntyre, Nancy E.; Chu, Yong-Kyu; Owen, Robert Dale; Abuzeineh, Alisa A.; Sancha, Noé U. de la; Dick, Carl W.; Holsomback, Tyla S.; Nisbett, Richard A.; Jonsson, Colleen B.

doi:10.4269/ajtmh.2005.73.1043

Cited by 40 publications

(52 citation statements)

References 35 publications

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“…However, especially noteworthy was the overrepresentation of MJNV infection among adult male Ussuri shrews, a pattern which has been reported previously for Seoul virus (SEOV) infection in the Norway rat (Rattus norvegicus) ( (9,14), and Bayou virus infection in the marsh rice rat (Oryzomys palustris) (35). Whether the male predominance among MJNV-infected shrews results from prolonged shedding of high-titered infectious virus in secretions and excretions or reflects intraspecies transmission through wounding, as reported for SEOV-infected rats (24), is unclear.…”

Section: Discussionmentioning

confidence: 91%

Characterization of Imjin Virus, a Newly Isolated Hantavirus from the Ussuri White-Toothed Shrew ( Crocidura lasiura )

Song

Kang

et al. 2009

J Virol

102

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Until recently, the single known exception to the rodent-hantavirus association was Thottapalayam virus (TPMV), a long-unclassified virus isolated from the Asian house shrew (Suncus murinus)Hantaviruses (family Bunyaviridae, genus Hantavirus) are medically important rodent-borne pathogens, causing hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS). The belief in long-standing coevolutionary relationships between hantaviruses and their reservoir rodent host species is supported by virus and rodent gene phylogenies. That is, phylogenetic analyses, based on full-length viral genomic sequences and rodent mitochondrial DNA (mtDNA) or nuclear gene sequences, indicate that antigenically distinct hantaviruses segregate into clades, which parallel the evolution of rodents in the subfamilies Murinae, Arvicolinae, Neotominae, and Sigmodontinae (23,25,26,28,39,54). Previously, this phylogenetic insight has been successfully employed to direct the discovery of new hantaviruses, such as those found in the Korean field mouse (Apodemus peninsulae) (5) and the royal vole (Myodes regulus) (47).Renewed interest in the role of nonrodent reservoirs in the evolution of hantaviruses has been spurred by recent analysis of the entire genome of Thottapalayam virus (TPMV), a hantavirus isolated from the Asian house shrew (Suncus murinus) (10, 61), which revealed a separate phylogenetic clade, suggesting early evolutionary divergence from rodent-borne hantaviruses (44, 56). Armed with oligonucleotide primers designed on the basis of conserved regions of the TPMV genome and guided by long-ignored reports of serologic and antigenic evidence of hantavirus infection in shrews (20, 33, 52), we have previously detected genetically distinct hantaviruses in the Eurasian common shrew (Sorex araneus) from Switzerland (45); the Chinese mole shrew (Anourosorex squamipes) from Vietnam (46); and the northern short-tailed shrew (Blarina brevicauda), masked shrew (Sorex cinereus), and dusky shrew (Sorex monticolus) from the United States (1, 2) by reverse transcription-PCR (RT-PCR). Novel hantavirus genomes in Therese's shrew (Crocidura theresae) from Guinea (29); the vagrant shrew (Sorex vagrans), Trowbridge's shrew (Sorex trowbridgii), and the American water shrew (Sorex palustris) from the United States (H. J. Kang and R. Yanagihara, unpublished data); and the flat-skulled shrew (Sorex roboratus) and Laxmann's shrew (Sorex caecutiens) from Russia (Kang and Yanagihara, unpublished) have also been detected.Here, we report the antigenic, genetic, and phylogenetic characterization of a newly identified hantavirus, designated Imjin virus (MJNV), isolated from Ussuri white-toothed shrews of the species Crocidura lasiura (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone (DMZ) in the Republic of Korea. The discovery of MJNV and other soricid-borne hantaviruses from widely separated geographic regions, spanning four continents,

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Section: Discussionmentioning

confidence: 91%

Characterization of Imjin Virus, a Newly Isolated Hantavirus from the Ussuri White-Toothed Shrew ( Crocidura lasiura )

Song

Kang

et al. 2009

J Virol

102

View full text Add to dashboard Cite

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“…It favours riparian and wetland habitats, is strictly nocturnal and prefers a carnivorous diet of fish, crustaceans, insects and the eggs and young of marsh birds and turtles, but will supplement its dietary needs with omnivory based on seasonal conspecific densities and plant phenologies. Empirical support for both macrohabitat and microhabitat selection in O. palustris has been described previously (Kincaid et al, 1983;McIntyre et al, 2005McIntyre et al, , 2009. Although little is known of the social relationships and behaviours of the marsh rice rat, it is believed to be solitary, aggressive and territorial, contingent upon population density and resource availability.…”

Section: Introductionmentioning

confidence: 99%

“…We noted breeding throughout the year (Goldman, 1918;McIntyre et al, 2005). An almost 1:1 ratio in terms of breeding and non-breeding females was revealed from all four grids (data not shown).…”

Section: Proportion Of Breeding To Non-breeding Females Degree Of Spmentioning

confidence: 99%

“…Collection permits were granted by the Texas Parks and Wildlife Department (permit #APR-0498-944 and #SPR-0504-381). Rodents were live-trapped on four mark-recapture rectangular grids 7100-7700 m 2 in size (traps placed at 10 m intervals and numbers of traps ranged from 93-113, contingent upon coastline topography and flooding) in two macrohabitat types (upland and coastal marshland, each with one replicate grid) for 4-6 consecutive nights for each of four seasons (mid-March, late May, late August, mid-December) during the 30-month study period (McIntyre et al, 2005) (Fig. 1).…”

Section: Mark-recapture Gridsmentioning

confidence: 99%

“…Protocols were developed and validated previously (Chu et al, 1995(Chu et al, , 2003. Stepwise details are in McIntyre et al (2005).…”

Section: Anti-bayv Igg Determination By Immunofluorescence Microscopymentioning

confidence: 99%

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Socio-ecology of the marsh rice rat (Oryzomys palustris) and the spatio-temporal distribution of Bayou virus in coastal Texas

et al. 2013

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Abstract. Along the southeastern coast of the United States of America (USA), the marsh rice rat (Oryzomys palustris) is the primary host for the hantavirus genotype Bayou. According to the socio-ecological model for a territorial, polygamous species, females should be distributed across space and time by habitat resources and predation risks, whereas males should space themselves according to the degree of female aggregation and reproductive synchrony. To investigate how females affect the male-male transmission paradigm of Bayou virus, rodents were captured, marked, released, and re-captured in two macrohabitat types across a 30-month period. Microhabitat cover variables were quantified around the individual trap stations. A geodatabase was created from habitat and rodent capture data and analysed in a geographical information system. The ratio of breeding to non-breeding females was ~1:1, with breeding females overly dispersed and non-breeding females randomly dispersed. Spatial analyses revealed both macro-and microhabitat preferences in females. Compared to sero-negatives, higher proportions of seropositive adult males were found consistently within closer proximities to breeding females but not to non-breeding females, indicating that male locations were not driven simply by habitat selection. Activities to acquire dispersed receptive females could be an important driver of Bayou virus transmission among male hosts. To date, socio-ecological theory has received little attention as an investigative framework for studying pathogen dynamics in small, solitary mammals. Herein, we describe an interdisciplinary effort providing a novel approach to elucidate the complexity of hantavirus trafficking and maintenance in rodent populations of a coastal marsh ecosystem.

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Sex and habitat drive hantavirus prevalence in marsh rice rat populations impacted by the Deepwater Horizon oil spill

et al. 2022

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Bayou orthohantavirus (BAYV) is one of several hantaviruses in the United States that cause hantavirus pulmonary syndrome in humans. Its host reservoir, the marsh rice rat (Oryzomys palustris), inhabits coastal saltmarshes of Louisiana, a region extensively impacted by anthropogenic disturbances, such as the 2010 Deepwater Horizon (DWH) oil spill. The oil spill presents an opportunity to investigate how a large-scale ecological disturbance can influence the hantavirus host-pathogen dynamic by examining BAYV presence in its reservoir host species in areas with different oiling histories. Here, we: (1) quantify BAYV prevalence in the rice rat in coastal saltmarshes of Louisiana; (2) assess whether prevalence is driven by rice rat demographics, seasonality, or association with habitat characteristics; and (3) determine whether these factors differ by marsh oiling history. We collected mark-recapture data and blood and tissue samples over 5 years (2013-2017) at oiled, unoiled, and reference sites. Testing of the samples for BAYV revealed an antibody and RNA prevalence of 13.7%. Logistic regression analysis found that prevalence varied seasonally and inter-annually, and in July of 2016 reached 30.8%. Sex (male) and increasing cover of Sporobolus alterniflorus and open water compared to Juncus roemerianus and bare ground were the strongest predictors of hantavirus prevalence. Abundance estimates derived from Huggins closed-capture models were greatest at oiled sites, but oiling treatment had no residual influence on BAYV prevalence, and abundance and prevalence were not correlated. This study supports the hypothesis that habitat is a main driver of hantavirus prevalence in the host and implies that continued and future disturbances in the region will likely impact the rice rat-BAYV dynamic by altering plant communities and landscape structure.

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A Longitudinal Study of Bayou Virus, Hosts, and Habitat

Cited by 40 publications

References 35 publications

Characterization of Imjin Virus, a Newly Isolated Hantavirus from the Ussuri White-Toothed Shrew ( Crocidura lasiura )

Characterization of Imjin Virus, a Newly Isolated Hantavirus from the Ussuri White-Toothed Shrew ( Crocidura lasiura )

Socio-ecology of the marsh rice rat (Oryzomys palustris) and the spatio-temporal distribution of Bayou virus in coastal Texas

Sex and habitat drive hantavirus prevalence in marsh rice rat populations impacted by the Deepwater Horizon oil spill

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