A long–term antimicrobial prophylaxis and/or immunotherapy in female patients with recurrent urinary tract infections

Abstract

Background: Infection involving the cerebrum is a true neurosurgical emergency that requires rapid diagnosis and appropriate surgical and medical intervention to achieve good clinical outcome.Methods: In this study we evaluated 41 pateints with brain abscess in our hospital in during 2005-2010. Demographic information, predisposing factors, clinical manifestations, lab. data and managements were evaluated.Results: In this study %53.6 of patients were 15-29 years old, %26 were 30-49 and %17 were 50-70 years old. Clinical manifestation was as follow in our study: Headache %92.6, nausea and vomiting %73.1, meningeal signs %17, drowsiness %12, decreased level of consciousness %9.7, fever %9.7, uninary and fecal incontinency % 7.3, visual disturbance % 7.3, chills %4.8. Predisposing condition leading to brain abscess in our study were sinusitis in %9.17, otitis in % 12, CSF rhinorrhea in % 2.4, mastoiditis in % 7.2, neurosurgery in % 17 and endocaiditis in %2.4. %20 of our patients had no risk factor. Antibiotics used in our study were ceftriaxne, metronidazole and vancomycin. Mortality rate was %12 in this study. % 9.7 of our patient that were admitted with diagnosis of brain abscess finally diagnosed as they had acute demyelinating encephalomyelitis (ADEM). Conclusion:With promp diagnosis and treatment most cases of brain abscess survived. Few cases initially diagnosed as brain abscess may have other diagnosis like acute demyelinating encephalomyelitis (ADEM).