A literature review of drug transport mechanisms during lactation
Christine Gong,
Lynn N. Bertagnolli,
David W. Boulton
et al.
Abstract:Despite the benefits of breastfeeding, lactating mothers who take prescribed medications may discontinue breastfeeding due to concerns associated with infant drug exposure in breastmilk. Consolidating the current knowledge of drug transport to breastmilk may inform understanding of the safety of medication use during lactation. This literature review summarizes the mechanisms of drug transport to breastmilk, details the physicochemical drug properties that may alter the extent of passive transport, and describ… Show more
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